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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Results:

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Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: Q02127

No.	Gene	UniProt ID	Protein Name	Pathway	PDB
1	DHODH	Q02127	Dihydroorotate dehydrogenase (quinone), mitochondrial	hsa00240; hsa01100	1D3G; 1D3H; 2B0M; 2BXV; 2FPT; 2FPV; 2FPY; 2FQI; 2PRH; 2PRL; 2PRM; 2WV8; 3F1Q; 3FJ6; 3FJL; 3G0U; 3G0X; 3KVJ; 3KVK; 3KVL; 3KVM; 3U2O; 3W7R; 3ZWS; 3ZWT; 4IGH; 4JGD; 4JS3; 4JTS; 4JTT; 4JTU; 4LS0; 4LS1; 4LS2; 4OQV; 4RK8; 4RKA; 4RLI

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Image
1	Experimental	SmallMoleculeDrug	DB08249	3,6,9,12,15-PENTAOXATRICOSAN-1-OL	CCCCCCCCOCCOCCOCCOCCOCCO
2	Approved; Investigational	SmallMoleculeDrug	DB01097	Leflunomide	CC1=C(C=NO1)C(=O)NC1=CC=C(C=C1)C(F)(F)F
3	Approved	SmallMoleculeDrug	DB08880	Teriflunomide	C\C(O)=C(/C#N)C(=O)NC1=CC=C(C=C1)C(F)(F)F
4	Experimental	SmallMoleculeDrug	DB08006	N-anthracen-2-yl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine	CC1=NC2=NC=NN2C(NC2=CC3=CC4=CC=CC=C4C=C3C=C2)=C1
5	Experimental	SmallMoleculeDrug	DB07977	3-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)THIOPHENE-2-CARBOXYLIC ACID	OC(=O)C1=C(C=CS1)C(=O)NC1=C(F)C=C(C=C1F)C1=CC(OC(F)(F)F)=CC=C1
6	Experimental	SmallMoleculeDrug	DB07559	(2Z)-2-cyano-N-(2,2'-dichlorobiphenyl-4-yl)-3-hydroxybut-2-enamide	C\C(O)=C(/C#N)C(=O)NC1=CC(Cl)=C(C=C1)C1=CC=CC=C1Cl
7	Experimental	SmallMoleculeDrug	DB07443	(2Z)-N-biphenyl-4-yl-2-cyano-3-hydroxybut-2-enamide	C\C(O)=C(/C#N)C(=O)NC1=CC=C(C=C1)C1=CC=CC=C1
8	Experimental	SmallMoleculeDrug	DB02613	Decylamine-N,N-Dimethyl-N-Oxide	CCCCCCCCCC[N+](C)(C)[O-]
9	Investigational	SmallMoleculeDrug	DB05125	SC12267	NA
10	Experimental	SmallMoleculeDrug	DB07976	3-{[(3-FLUORO-3'-METHOXYBIPHENYL-4-YL)AMINO]CARBONYL}THIOPHENE-2-CARBOXYLIC ACID	COC1=CC=CC(=C1)C1=CC=C(NC(=O)C2=C(SC=C2)C(O)=O)C(F)=C1
11	Approved; Investigational	SmallMoleculeDrug	DB03247	Flavin mononucleotide	CC1=CC2=C(C=C1C)N(C[C@H](O)[C@H](O)[C@H](O)COP(O)(O)=O)C1=NC(=O)NC(=O)C1=N2
12	Experimental	SmallMoleculeDrug	DB08008	5-methyl-N-[4-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine	CC1=NC2=NC=NN2C(NC2=CC=C(C=C2)C(F)(F)F)=C1
13	Approved	SmallMoleculeDrug	DB01117	Atovaquone	OC1=C([C@H]2CC[C@@H](CC2)C2=CC=C(Cl)C=C2)C(=O)C2=CC=CC=C2C1=O
14	Experimental	SmallMoleculeDrug	DB03480	Brequinar Analog	CC1=C(N=C2C=CC(F)=CC2=C1C(O)=O)C1=CC=C(C=C1)C1=CC=CC=C1
15	Experimental	SmallMoleculeDrug	DB03523	Brequinar	CC1=C(N=C2C=CC(F)=CC2=C1C(O)=O)C1=CC=C(C=C1)C1=CC=CC=C1F
16	Experimental	SmallMoleculeDrug	DB04583	5-Carbamoyl-1,1':4',1''-terphenyl-3-carboxylic acid	NC(=O)C1=CC(=CC(=C1)C1=CC=C(C=C1)C1=CC=CC=C1)C(O)=O
17	Experimental	SmallMoleculeDrug	DB04147	Lauryl Dimethylamine-N-Oxide	CCCCCCCCCCCC[N+](C)(C)[O-]
18	Experimental	SmallMoleculeDrug	DB07975	2-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID	OC(=O)C1=C(CCC1)C(=O)NC1=C(F)C=C(C=C1F)C1=CC=CC(OC(F)(F)F)=C1
19	Experimental	SmallMoleculeDrug	DB04281	2-[4-(4-Chlorophenyl)Cyclohexylidene]-3,4-Dihydroxy-1(2h)-Naphthalenone	[H]C1(CCC(CC1)=C1C(O)=C(O)C2=CC=CC=C2C1=O)C1=CC=C(Cl)C=C1
20	Experimental	SmallMoleculeDrug	DB08172	(2Z)-N-(3-chloro-2'-methoxybiphenyl-4-yl)-2-cyano-3-hydroxybut-2-enamide	COC1=CC=CC=C1C1=CC(Cl)=C(NC(=O)C(\C#N)=C(\C)O)C=C1
21	Experimental	SmallMoleculeDrug	DB07978	2-({[2,3,5,6-TETRAFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENTA-1,3-DIENE-1-CARBOXYLIC ACID	OC(=O)C1=C(C=CC1)C(=O)NC1=C(F)C(F)=C(C(F)=C1F)C1=CC(OC(F)(F)F)=CC=C1
22	Experimental	SmallMoleculeDrug	DB08169	(2Z)-N-biphenyl-4-yl-2-cyano-3-cyclopropyl-3-hydroxyprop-2-enamide	O\C(C1CC1)=C(\C#N)C(=O)NC1=CC=C(C=C1)C1=CC=CC=C1
23	Investigational	SmallMoleculeDrug	DB06481	Manitimus	O\C(CCC#C)=C(\C#N)C(=O)NC1=CC=C(C=C1)C(F)(F)F
24	Experimental	SmallMoleculeDrug	DB07561	(2Z)-2-cyano-N-(3'-ethoxybiphenyl-4-yl)-3-hydroxybut-2-enamide	CCOC1=CC(=CC=C1)C1=CC=C(NC(=O)C(\C#N)=C(\C)O)C=C1
25	Experimental	SmallMoleculeDrug	DB07646	UNDECYLAMINE-N,N-DIMETHYL-N-OXIDE	CCCCCCCCCCC[N+](C)(C)[O-]
26	Experimental; Investigational	SmallMoleculeDrug	DB02262	Orotic Acid	OC(=O)C1=CC(=O)NC(=O)N1

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Image	Confidence score
1	Approved; Nutraceutical	SmallMoleculeDrug	DB00142	Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O		49.0%
2	Approved; Experimental; Investigational	SmallMoleculeDrug	DB02709	Resveratrol	OC1=CC=C(\C=C\C2=CC(O)=CC(O)=C2)C=C1		34.7%
3	Experimental	SmallMoleculeDrug	DB03738	Pantothenoylaminoethenethiol	[H]\C(S)=C(/[H])N=C(O)CCN=C(O)[C@]([H])(O)C(C)(C)CO		29.5%
4	Approved; Investigational	SmallMoleculeDrug	DB05541	Brivaracetam	CCC[C@H]1CN([C@@H](CC)C(N)=O)C(=O)C1		29.4%
5	Approved; Investigational	SmallMoleculeDrug	DB00952	Naratriptan	CNS(=O)(=O)CCC1=CC2=C(NC=C2C2CCN(C)CC2)C=C1		27.3%
6	Experimental	SmallMoleculeDrug	DB08515	(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE	[H][C@](O)([C@@]1([H])CCCC=C1)[C@]1(NC(=O)[C@]2([H])CCO[C@]12C)C=O		27.0%
7	Experimental	SmallMoleculeDrug	DB04522	Dexfosfoserine	N[C@@H](COP(O)(O)=O)C(O)=O		26.8%
8	Approved	BiotechDrug	DB00071	Insulin Pork	NA		26.7%
9	Approved; Investigational	SmallMoleculeDrug	DB03088	Pidolic Acid	OC(=O)[C@@H]1CCC(=O)N1		26.3%
10	Experimental	SmallMoleculeDrug	DB03721	N-acetyl-alpha-neuraminic acid	[H][C@]1(O[C@](O)(C[C@H](O)[C@H]1NC(C)=O)C(O)=O)[C@H](O)[C@H](O)CO		25.6%
11	Investigational	SmallMoleculeDrug	DB12695	Phenethyl Isothiocyanate	S=C=NCCC1=CC=CC=C1		25.3%
12	Investigational	SmallMoleculeDrug	DB12961	Leukotriene B4	CCCCC\C=C/C[C@@H](O)\C=C\C=C\C=C/[C@@H](O)CCCC(O)=O		25.1%
13	Approved; Investigational	SmallMoleculeDrug	DB09568	Omega-3-carboxylic acids	NA		25.0%
14	Approved; Investigational	BiotechDrug	DB00030	Insulin Human	NA		24.7%
15	Approved; Investigational	SmallMoleculeDrug	DB00571	Propranolol	CC(C)NCC(O)COC1=CC=CC2=CC=CC=C12		24.7%
16	Experimental	SmallMoleculeDrug	DB08235	N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide	CC1=C(CCNC(=O)C2=CC=CS2)C2=CC=CC=C2N1		24.5%
17	Experimental	SmallMoleculeDrug	DB08175	(2E,4E)-11-METHOXY-3,7,11-TRIMETHYLDODECA-2,4-DIENOIC ACID	COC(C)(C)CCC[C@@](C)([H])C\C=C\C(\C)=C\C(O)=O		24.4%
18	Approved; Vet approved	SmallMoleculeDrug	DB08818	Hyaluronic acid	CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)C1O[C@@H]1O[C@@H]([C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)C(O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(O)=O)[C@H]2NC(C)=O)[C@H](O)[C@H]1O)C(O)=O		24.2%
19	Experimental	SmallMoleculeDrug	DB07664	5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE	NC1=NC(NC2=CC=C(C=C2)S(N)(=O)=O)=NN1C(=S)NC1=C(F)C=CC=C1F		24.2%
20	Approved; Nutraceutical	SmallMoleculeDrug	DB00132	Alpha-Linolenic Acid	CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O		24.1%