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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: P00326
No. Gene UniProt ID Protein Name Pathway PDB
1 ADH1C P00326 Alcohol dehydrogenase 1C hsa00010; hsa00071; hsa00350; hsa00830; hsa00980; hsa00982; hsa01100; hsa05204 1DDA; 1HT0; 1U3W

18 known interactions (drugs) of input target (ADH1C): Alcohol dehydrogenase 1C
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter
1 Approved;
Vet approved
SmallMoleculeDrug DB01213 Fomepizole Thumb
2 Experimental SmallMoleculeDrug DB02871 3-Butylthiolane 1-Oxide Thumb
3 Experimental SmallMoleculeDrug DB03559 Cyclohexylformamide Thumb
4 Experimental SmallMoleculeDrug DB02757 Pyrazole Thumb
5 Experimental SmallMoleculeDrug DB04113 N-Formylpiperidine Thumb
6 Experimental SmallMoleculeDrug DB02721 4-Iodopyrazole Thumb
7 Experimental SmallMoleculeDrug DB01711 2,3,4,5,6-Pentafluorobenzyl Alcohol Thumb
8 Experimental SmallMoleculeDrug DB02822 Para-Bromobenzyl Alcohol Thumb
9 Experimental SmallMoleculeDrug DB04071 Cpad Thumb
10 Experimental SmallMoleculeDrug DB03226 Trifluoroethanol Thumb
11 Approved SmallMoleculeDrug DB02659 Cholic Acid Thumb
12 Approved;
SmallMoleculeDrug DB00157 NADH Thumb
13 Experimental SmallMoleculeDrug DB02131 N-1-Methylheptylformamide Thumb
14 Experimental SmallMoleculeDrug DB03020 5-Beta-D-Ribofuranosylnicotinamide Adenine Dinucleotide Thumb
15 Experimental SmallMoleculeDrug DB03061 (R)-N-(1-Methyl-Hexyl)-Formamide Thumb
16 Experimental SmallMoleculeDrug DB04448 2,4-Difluorobenzyl Alcohol 2,4-Difluoro-1-(Hydroxymethyl)Benzene Thumb
17 Experimental SmallMoleculeDrug DB02249 2-Ethoxyethanol Thumb
18 Experimental SmallMoleculeDrug DB04312 2,3-Difluorobenzyl Alcohol Thumb

20 predicted interactions (drugs) of input target (ADH1C): Alcohol dehydrogenase 1C
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter
Image Confidence score
1 Experimental SmallMoleculeDrug DB04464 N-Formylmethionine Thumb 39.7%
2 Approved SmallMoleculeDrug DB03147 Flavin adenine dinucleotide Thumb 32.8%
3 Approved BiotechDrug DB00098 Antithymocyte immunoglobulin (rabbit) Thumb 31.3%
4 Approved;
SmallMoleculeDrug DB12010 Fostamatinib Thumb 28.1%
5 Experimental SmallMoleculeDrug DB08231 Myristic acid Thumb 27.5%
6 Approved;
SmallMoleculeDrug DB00172 L-Proline Thumb 27.4%
7 Approved;
SmallMoleculeDrug DB00313 Valproic Acid Thumb 26.8%
8 Approved SmallMoleculeDrug DB06777 Chenodeoxycholic acid Thumb 26.4%
9 Approved BiotechDrug DB00031 Tenecteplase Thumb 25.2%
10 Experimental SmallMoleculeDrug DB04137 Guanosine-5'-Triphosphate Thumb 24.7%
11 Approved;
SmallMoleculeDrug DB11967 Binimetinib Thumb 23.9%
12 Approved;
SmallMoleculeDrug DB01593 Zinc Thumb 23.1%
13 Approved;
SmallMoleculeDrug DB08889 Carfilzomib Thumb 22.9%
14 Approved;
SmallMoleculeDrug DB03615 Ribostamycin Thumb 22.6%
15 Approved;
SmallMoleculeDrug DB09130 Copper Thumb 22.2%
16 Approved;
SmallMoleculeDrug DB00125 L-Arginine Thumb 22.2%
17 Experimental SmallMoleculeDrug DB04604 5-iodotubercidin Thumb 22.2%
18 Approved;
SmallMoleculeDrug DB08901 Ponatinib Thumb 22.0%
19 Investigational SmallMoleculeDrug DB01645 Genistein Thumb 22.0%
20 Experimental SmallMoleculeDrug DB02059 Adenosine-5-Diphosphoribose Thumb 21.8%


Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.


The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.