QuartataWeb 1.0

28 known interactions (drugs) of input target (RNASE1): Ribonuclease pancreatic

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter
1	Experimental	SmallMoleculeDrug	DB03155	1-(2-Deoxy-2-Fluoro-3-O-Phosphono-Beta-L-Ribofuranosyl)Pyrimidine-2,4(1h,3h)-Dione	[H][C@]1(CO)O[C@@]([H])(N2C=CC(O)=NC2=O)[C@]([H])(F)[C@]1([H])OP(O)(O)=O
2	Experimental	SmallMoleculeDrug	DB01842	3'-Phosphate-Adenosine-5'-Diphosphate	[H][C@]1(COP(O)(=O)OP(O)(O)=O)O[C@@]([H])(N2C=NC3=C(N)N=CN=C23)[C@]([H])(O)[C@]1([H])OP(O)(O)=O
3	Experimental	SmallMoleculeDrug	DB08661	1-(2,5-dideoxy-5-pyrrolidin-1-yl-beta-L-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione	[H][C@@]1(O)C[C@]([H])(O[C@@]1([H])CN1CCCC1)N1C=C(C)C(=O)NC1=O
4	Experimental	SmallMoleculeDrug	DB02714	3'-Uridinemonophosphate	[H][C@]1(CO)O[C@@]([H])(N2C=CC(O)=NC2=O)[C@]([H])(O)[C@]1([H])OP(O)(O)=O
5	Experimental	SmallMoleculeDrug	DB04464	N-Formylmethionine	[H][C@@](CCSC)(NC=O)C(O)=O
6	Experimental	SmallMoleculeDrug	DB03726	Purine Riboside-5'-Monophosphate	[H][C@]1(COP(O)(O)=O)O[C@@]([H])(N2C=NC3=CN=CN=C23)[C@]([H])(O)[C@]1([H])O
7	Experimental	SmallMoleculeDrug	DB03512	Uridine-2',3'-Vanadate	OC[C@@H]1O[C@H]([C@H]2O[V](O)(O)(=O)O[C@H]12)N1C=CC(=O)NC1=O
8	Approved; Experimental; Investigational	SmallMoleculeDrug	DB01942	Formic Acid	OC=O
9	Experimental	SmallMoleculeDrug	DB03186	U-Pi-a-Pi	[H][C@@]1(C[C@]([H])(OP(O)(=O)OP(O)(=O)OC[C@@]2([H])O[C@@]([H])(N3C=NC4=C(N)N=CN=C34)[C@]([H])(O)[C@]2([H])OP(O)(O)=O)[C@@]([H])(COP(O)(O)=O)O1)N1C=CC(O)=NC1=O
10	Experimental	SmallMoleculeDrug	DB03326	deoxycytidylyl-3',5'-guanosine	[H][C@]1(O)C[C@@]([H])(O[C@]1([H])COP(O)(=O)OC1([H])CC([H])(OC1([H])CO)N1C=CC(=N)N=C1O)N1C=NC2=C1NC(=N)N=C2O
11	Experimental	SmallMoleculeDrug	DB02363	2'-Monophosphoadenosine-5'-Diphosphate	[H][C@]1(COP(O)(=O)OP(O)(O)=O)O[C@@]([H])(N2C=NC3=C(N)N=CN=C23)[C@]([H])(OP(O)(O)=O)[C@]1([H])O
12	Experimental	SmallMoleculeDrug	DB03448	2'-Deoxyuridine 3'-Monophosphate	OC[C@H]1O[C@H](C[C@@H]1OP(O)(O)=O)N1C=CC(=O)NC1=O
13	Approved; Nutraceutical; Vet approved	SmallMoleculeDrug	DB04272	Citric Acid	OC(=O)CC(O)(CC(O)=O)C(O)=O
14	Experimental	SmallMoleculeDrug	DB02098	Adenosine-2'-5'-Diphosphate	[H][C@]1(COP(O)(O)=O)O[C@@]([H])(N2C=NC3=C(N)N=CN=C23)[C@]([H])(OP(O)(O)=O)[C@]1([H])O
15	Experimental	SmallMoleculeDrug	DB04514	Phosphoric Acid-2'-[2'-Deoxy-Uridine]Ester-5'-Guanosine Ester	[H][C@]1(CO)O[C@@]([H])(N2C=CC(O)=NC2=O)[C@]([H])(OP(O)(=O)OC[C@@]2([H])O[C@@]([H])(N3C=NC4=C3NC(=N)N=C4O)[C@]([H])(O)[C@]2([H])O)[C@]1([H])O
16	Experimental	SmallMoleculeDrug	DB01812	Adenosine-3'-5'-Diphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H]1O
17	Experimental	SmallMoleculeDrug	DB03900	2-Methyl-2-Propanol	CC(C)(C)O
18	Experimental	SmallMoleculeDrug	DB02573	2'-Deoxycytidine-2'-Deoxyadenosine-3',5'-Monophosphate	[H][C@]1(O)C[C@@]([H])(O[C@]1([H])COP(O)(=O)O[C@@]1([H])C[C@@]([H])(O[C@]1([H])CO)N1C=CC(=N)N=C1O)N1C=NC2=C(N)N=CN=C12
19	Experimental	SmallMoleculeDrug	DB08596	5'-deoxy-5'-piperidin-1-ylthymidine	[H][C@]1(O)C[C@@]([H])(O[C@]1([H])CN1CCCCC1)N1C=C(C)C(=O)NC1=O
20	Experimental	SmallMoleculeDrug	DB03447	Uridylyl-2'-5'-Phospho-Adenosine	[H][C@]1(CO)O[C@@]([H])(N2C=CC(O)=NC2=O)[C@]([H])(OP(O)(=O)OC[C@@]2([H])O[C@@]([H])(N3C=NC4=C(N)N=CN=C34)[C@]([H])(O)[C@]2([H])O)[C@]1([H])O
21	Experimental	SmallMoleculeDrug	DB02987	Cysteine-S-Acetamide	N[C@@H](CSCC(N)=O)C(O)=O
22	Experimental	SmallMoleculeDrug	DB01961	Cytidine 3'-monophosphate	[H][C@]1(CO)O[C@@]([H])(N2C=CC(=N)N=C2O)[C@]([H])(O)[C@]1([H])OP(O)(O)=O
23	Approved	SmallMoleculeDrug	DB00536	Guanidine	NC(N)=N
24	Approved; Nutraceutical	SmallMoleculeDrug	DB00128	L-Aspartic Acid	N[C@@H](CC(O)=O)C(O)=O
25	Experimental	SmallMoleculeDrug	DB03765	2'-cytidylic acid	[H][C@]1(CO)O[C@@]([H])(N2C=CC(=N)N=C2O)[C@]([H])(OP(O)(O)=O)[C@]1([H])O
26	Experimental	SmallMoleculeDrug	DB03792	5-Amino-1h-Pyrimidine-2,4-Dione	NC1=CNC(=O)NC1=O
27	Approved; Investigational	SmallMoleculeDrug	DB02325	Isopropyl Alcohol	CC(C)O
28	Experimental	SmallMoleculeDrug	DB02805	Uracil arabinose-3'-phosphate	[H][C@]1(CO)O[C@@]([H])(N2C=CC(O)=NC2=O)[C@@]([H])(O)[C@]1([H])OP(O)(O)=O

20 predicted interactions (drugs) of input target (RNASE1): Ribonuclease pancreatic

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Confidence score
1	Approved; Investigational	SmallMoleculeDrug	DB09130	Copper	[Cu]	43.0%
2	Approved	SmallMoleculeDrug	DB02659	Cholic Acid	[H][C@@](C)(CCC(O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@]([H])(O)C[C@]4([H])C[C@]([H])(O)CC[C@]4(C)[C@@]3([H])C[C@]([H])(O)[C@]12C	30.5%
3	Experimental	SmallMoleculeDrug	DB04447	1,4-Dithiothreitol	O[C@@H](CS)[C@@H](O)CS	29.8%
4	Experimental; Investigational	SmallMoleculeDrug	DB02745	Uridine	OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(=O)NC1=O	28.7%
5	Experimental	SmallMoleculeDrug	DB04493	Fructose-6-Phosphate	OCC(=O)[C@@H](O)[C@H](O)[C@H](O)COP(O)(O)=O	28.5%
6	Experimental	SmallMoleculeDrug	DB03435	Uridine-5'-Diphosphate	O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(O)=O)N1C=CC(=O)NC1=O	25.7%
7	Approved; Experimental; Investigational	SmallMoleculeDrug	DB02709	Resveratrol	OC1=CC=C(\C=C\C2=CC(O)=CC(O)=C2)C=C1	25.6%
8	Approved; Investigational	SmallMoleculeDrug	DB01593	Zinc	[Zn]	25.5%
9	Experimental	SmallMoleculeDrug	DB03459	Sparfosic acid	[H][C@@](CC(O)=O)(N=C(O)CP(O)(O)=O)C(O)=O	25.2%
10	Approved; Investigational; Withdrawn	BiotechDrug	DB00013	Urokinase	NA	25.0%
11	Experimental	SmallMoleculeDrug	DB01972	Guanosine-5'-Monophosphate	NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1	24.9%
12	Approved; Investigational	SmallMoleculeDrug	DB11638	Artenimol	[H][C@@]1(C)CC[C@@]2([H])[C@@]([H])(C)C([H])(O)O[C@]3([H])O[C@@]4(C)CC[C@]1([H])[C@@]23OO4	24.8%
13	Approved; Experimental	SmallMoleculeDrug	DB03017	Lauric Acid	CCCCCCCCCCCC(O)=O	24.4%
14	Investigational	BiotechDrug	DB06245	Lanoteplase	NA	24.4%
15	Experimental	SmallMoleculeDrug	DB07841	Geranylgeranyl diphosphate	CC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCOP(O)(=O)OP(O)(O)=O	24.1%
16	Approved; Nutraceutical	SmallMoleculeDrug	DB01373	Calcium	[Ca]	23.9%
17	Approved; Investigational	SmallMoleculeDrug	DB03088	Pidolic Acid	OC(=O)[C@@H]1CCC(=O)N1	23.7%
18	Approved; Investigational	SmallMoleculeDrug	DB00290	Bleomycin	C[C@@H](O)[C@H](NC(=O)[C@@H](C)[C@H](O)[C@@H](C)NC(=O)[C@@H](NC(=O)C1=C(C)C(N)=NC(=N1)[C@H](CC(N)=O)NC[C@H](N)C(N)=O)[C@@H](OC1OC(CO)C(O)C(O)C1OC1OC(CO)C(O)C(OC(N)=O)C1O)C1=CN=CN1)C(=O)NCCC1=NC(=CS1)C1=NC(=CS1)C(=O)NCCC[S+](C)C	23.2%
19	Experimental	SmallMoleculeDrug	DB02783	4'-Deoxy-4'-Acetylyamino-Pyridoxal-5'-Phosphate	CC1=NC=C(COP(O)(O)=O)C(CNOCC(O)=O)=C1O	23.0%
20	Experimental	SmallMoleculeDrug	DB02548	D-glucitol 6-phosphate	OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)COP(O)(O)=O	23.0%