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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Results:

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Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: P01375

No.	Gene	UniProt ID	Protein Name	Pathway	PDB
1	TNF	P01375	Tumor necrosis factor	hsa01523; hsa04010; hsa04060; hsa04064; hsa04071; hsa04150; hsa04210; hsa04217; hsa04350; hsa04380; hsa04612; hsa04620; hsa04621; hsa04622; hsa04625; hsa04640; hsa04650; hsa04657; hsa04660; hsa04664; hsa04668; hsa04920; hsa04930; hsa04931; hsa04932; hsa04933; hsa04940; hsa05010; hsa05014; hsa05133; hsa05134; hsa05140; hsa05142; hsa05143; hsa05144; hsa05145; hsa05146; hsa05152; hsa05160; hsa05161; hsa05163; hsa05164; hsa05165; hsa05166; hsa05168; hsa05170; hsa05205; hsa05310; hsa05321; hsa05322; hsa05323; hsa05330; hsa05332; hsa05410; hsa05414; hsa05418	1A8M; 1TNF; 2AZ5; 2E7A; 2TUN; 2ZJC; 2ZPX; 3ALQ; 3IT8; 3L9J; 3WD5; 4G3Y; 4TSV; 4TWT; 5TSW

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Image
1	Investigational	SmallMoleculeDrug	DB05412	Talmapimod	[H][C@]1(C)CN(C(=O)C2=C(Cl)C=C3N(C)C=C(C(=O)C(=O)N(C)C)C3=C2)[C@]([H])(C)CN1CC1=CC=C(F)C=C1
2	Approved; Investigational; Vet approved	SmallMoleculeDrug	DB01407	Clenbuterol	CC(C)(C)NCC(O)C1=CC(Cl)=C(N)C(Cl)=C1
3	Approved	BiotechDrug	DB10772	Foreskin keratinocyte (neonatal)	NA
4	Approved; Vet approved	SmallMoleculeDrug	DB00668	Epinephrine	CNC[C@H](O)C1=CC(O)=C(O)C=C1
5	Investigational	SmallMoleculeDrug	DB05017	YSIL6	NA
6	Approved; Investigational	SmallMoleculeDrug	DB01296	Glucosamine	N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O
7	Investigational	SmallMoleculeDrug	DB05513	Atiprimod	CCCC1(CCC)CCC2(CCN(CCCN(CC)CC)C2)CC1
8	Investigational	SmallMoleculeDrug	DB05207	SD118	NA
9	Investigational	SmallMoleculeDrug	DB05303	OMS-103HP	NA
10	Investigational	SmallMoleculeDrug	DB05869	Ethyl pyruvate	CCOC(=O)C(C)=O
11	Approved	SmallMoleculeDrug	DB01427	Amrinone	NC1=CC(=CNC1=O)C1=CC=NC=C1
12	Approved; Experimental	SmallMoleculeDrug	DB13751	Glycyrrhizic acid	[H][C@@]12C[C@](C)(CC[C@]1(C)CC[C@]1(C)C2=CC(=O)[C@]2([H])[C@@]3(C)CC[C@H](O[C@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O[C@@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)C(O)=O)C(O)=O)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O
13	Approved	SmallMoleculeDrug	DB08910	Pomalidomide	NC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O
14	Investigational	BiotechDrug	DB05218	PN0621	NA
15	Approved; Investigational; Vet approved	SmallMoleculeDrug	DB00608	Chloroquine	CCN(CC)CCCC(C)NC1=C2C=CC(Cl)=CC2=NC=C1
16	Approved	SmallMoleculeDrug	DB00852	Pseudoephedrine	CN[C@@H](C)[C@@H](O)C1=CC=CC=C1
17	Approved; Investigational	SmallMoleculeDrug	DB09221	Polaprezinc	[Zn++].[H][C@@](CC1=CN=CN1)([N-]C(=O)CCN)C([O-])=O
18	Approved; Investigational	BiotechDrug	DB00005	Etanercept	NA
19	Investigational	SmallMoleculeDrug	DB05470	VX-702	NC(=O)N(C1=CC=C(C(N)=O)C(=N1)C1=CC=C(F)C=C1F)C1=C(F)C=CC=C1F
20	Approved; Investigational	SmallMoleculeDrug	DB11967	Binimetinib	CN1C=NC2=C(F)C(NC3=CC=C(Br)C=C3F)=C(C=C12)C(=O)NOCCO
21	Approved	BiotechDrug	DB06674	Golimumab	NA
22	Investigational	SmallMoleculeDrug	DB05968	PR-104	CS(=O)(=O)OCCN(CCBr)C1=C(C=C(C=C1[N+]([O-])=O)[N+]([O-])=O)C(=O)NCCOP(O)(O)=O
23	Investigational	SmallMoleculeDrug	DB12140	Dilmapimod	CC1=CC(F)=CC=C1C1=C2C=CC(=O)N(C2=NC(NC(CO)CO)=N1)C1=C(F)C=CC=C1F
24	Approved	BiotechDrug	DB00051	Adalimumab	NA
25	Approved; Investigational; Withdrawn	SmallMoleculeDrug	DB01041	Thalidomide	O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC=CC=C12
26	Investigational	BiotechDrug	DB06495	Onercept	NA
27	Approved	BiotechDrug	DB10770	Foreskin fibroblast (neonatal)	NA
28	Investigational	SmallMoleculeDrug	DB06444	Dexanabinol	CCCCCCC(C)(C)C1=CC(O)=C2[C@H]3CC(CO)=CC[C@@H]3C(C)(C)OC2=C1
29	Investigational	SmallMoleculeDrug	DB05744	CRx-139	NA
30	Investigational	BiotechDrug	DB05879	AME-527	NA
31	Investigational	SmallMoleculeDrug	DB05992	Plinabulin	CC(C)(C)C1=C(\C=C2/NC(=O)\C(NC2=O)=C\C2=CC=CC=C2)N=CN1
32	Approved; Investigational	SmallMoleculeDrug	DB01411	Pranlukast	O=C(NC1=C2OC(=CC(=O)C2=CC=C1)C1=NNN=N1)C1=CC=C(OCCCCC2=CC=CC=C2)C=C1
33	Approved; Investigational	SmallMoleculeDrug	DB05676	Apremilast	[H][C@](CS(C)(=O)=O)(N1C(=O)C2=C(C1=O)C(=CC=C2)N=C(C)O)C1=CC(OCC)=C(OC)C=C1
34	Approved; Investigational	SmallMoleculeDrug	DB02325	Isopropyl Alcohol	CC(C)O
35	Investigational	SmallMoleculeDrug	DB05767	Andrographolide	[H]\C(C[C@]1([H])C(=C)CC[C@]2([H])[C@](C)(CO)[C@]([H])(O)CC[C@@]12C)=C1/C(=O)OC[C@@]1([H])O
36	Approved	BiotechDrug	DB00065	Infliximab	NA
37	Investigational	BiotechDrug	DB05758	CYT007-TNFQb	NA
38	Investigational	BiotechDrug	DB04956	Afelimomab	NA
39	Approved	BiotechDrug	DB08904	Certolizumab pegol	NA

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Image	Confidence score
1	Experimental	SmallMoleculeDrug	DB08342	S-PALMITOYL-L-CYSTEINE	[H][C@](N)(CSC(=O)CCCCCCCCCCCCCCC)C(O)=O		48.5%
2	Approved; Investigational	BiotechDrug	DB09036	Siltuximab	NA		42.9%
3	Approved; Investigational; Nutraceutical	SmallMoleculeDrug	DB01404	Ginseng	NA		42.4%
4	Approved; Investigational	BiotechDrug	DB00072	Trastuzumab	NA		38.2%
5	Approved; Investigational	SmallMoleculeDrug	DB01017	Minocycline	[H][C@@]12CC3=C(C(O)=CC=C3N(C)C)C(=O)C1=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@]1([H])C2		37.6%
6	Approved; Investigational	BiotechDrug	DB00074	Basiliximab	NA		36.9%
7	Approved; Investigational	SmallMoleculeDrug	DB01593	Zinc	[Zn]		36.6%
8	Approved	BiotechDrug	DB00002	Cetuximab	NA		35.3%
9	Investigational	SmallMoleculeDrug	DB06083	Tapinarof	CC(C)C1=C(O)C=C(\C=C\C2=CC=CC=C2)C=C1O		34.7%
10	Approved; Investigational; Vet approved	SmallMoleculeDrug	DB01392	Yohimbine	[H][C@@]12CC[C@H](O)[C@H](C(=O)OC)[C@@]1([H])C[C@]1([H])N(CCC3=C1NC1=CC=CC=C31)C2		34.6%
11	Approved; Investigational	BiotechDrug	DB06168	Canakinumab	NA		31.1%
12	Approved; Investigational	BiotechDrug	DB00075	Muromonab	NA		30.6%
13	Experimental; Investigational	SmallMoleculeDrug	DB03496	Alvocidib	CN1CC[C@@H]([C@H](O)C1)C1=C(O)C=C(O)C2=C1OC(=CC2=O)C1=CC=CC=C1Cl		30.0%
14	Approved; Investigational; Withdrawn	BiotechDrug	DB06607	Catumaxomab	NA		28.5%
15	Experimental	SmallMoleculeDrug	DB07636	5-HEPTYL-6-HYDROXY-1,3-BENZOTHIAZOLE-4,7-DIONE	CCCCCCCC1=C(O)C(=O)C2=C(N=CS2)C1=O		27.7%
16	Approved	SmallMoleculeDrug	DB00502	Haloperidol	OC1(CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1)C1=CC=C(Cl)C=C1		27.3%
17	Investigational	BiotechDrug	DB05110	VIR201	NA		26.5%
18	Experimental	SmallMoleculeDrug	DB08453	2-NONYL-4-HYDROXYQUINOLINE N-OXIDE	CCCCCCCCCC1=[N+]([O-])C2=CC=CC=C2C(O)=C1		26.2%
19	Approved; Investigational	BiotechDrug	DB00112	Bevacizumab	NA		26.2%
20	Approved; Investigational	BiotechDrug	DB00028	Immune Globulin Human	NA		26.1%