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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: O00204
No. Gene UniProt ID Protein Name Pathway PDB
1 SULT2B1 O00204 Sulfotransferase family cytosolic 2B member 1 hsa00140 1Q1Q; 1Q1Z; 1Q20; 1Q22


4 known interactions (drugs) of input target (SULT2B1): Sulfotransferase family cytosolic 2B member 1
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image
1 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB01708 Prasterone Thumb
2 Experimental SmallMoleculeDrug DB03309 N-Cyclohexyltaurine Thumb
3 Experimental SmallMoleculeDrug DB01812 Adenosine-3'-5'-Diphosphate Thumb
4 Approved;
Experimental;
Investigational		 SmallMoleculeDrug DB02789 Pregnenolone Thumb


20 predicted interactions (drugs) of input target (SULT2B1): Sulfotransferase family cytosolic 2B member 1
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image Confidence score
1 Approved;
Nutraceutical;
Vet approved		 SmallMoleculeDrug DB00145 Glycine Thumb 39.2%
2 Approved;
Investigational		 SmallMoleculeDrug DB12010 Fostamatinib Thumb 35.2%
3 Approved;
Investigational;
Vet approved		 SmallMoleculeDrug DB00312 Pentobarbital Thumb 35.0%
4 Approved;
Withdrawn		 SmallMoleculeDrug DB00431 Lindane Thumb 34.7%
5 Approved;
Investigational		 SmallMoleculeDrug DB01174 Phenobarbital Thumb 33.6%
6 Approved;
Vet approved		 SmallMoleculeDrug DB01159 Halothane Thumb 31.6%
7 Approved;
Vet approved		 SmallMoleculeDrug DB00418 Secobarbital Thumb 27.6%
8 Approved;
Investigational		 SmallMoleculeDrug DB00659 Acamprosate Thumb 27.1%
9 Approved;
Investigational		 SmallMoleculeDrug DB11582 Thiocolchicoside Thumb 26.8%
10 Approved SmallMoleculeDrug DB13146 Fluciclovine (18F) Thumb 26.7%
11 Approved;
Illicit		 SmallMoleculeDrug DB00371 Meprobamate Thumb 25.0%
12 Withdrawn SmallMoleculeDrug DB07931 Hexestrol Thumb 25.0%
13 Approved SmallMoleculeDrug DB01595 Nitrazepam Thumb 24.9%
14 Approved;
Illicit		 SmallMoleculeDrug DB01559 Clotiazepam Thumb 24.5%
15 Approved;
Illicit		 SmallMoleculeDrug DB01068 Clonazepam Thumb 24.5%
16 Approved SmallMoleculeDrug DB00849 Methylphenobarbital Thumb 23.8%
17 Approved;
Investigational;
Vet approved		 SmallMoleculeDrug DB00783 Estradiol Thumb 23.4%
18 Approved;
Withdrawn		 SmallMoleculeDrug DB04824 Phenolphthalein Thumb 23.1%
19 Withdrawn SmallMoleculeDrug DB00463 Metharbital Thumb 23.0%
20 Approved;
Investigational;
Vet approved		 SmallMoleculeDrug DB13954 Estradiol cypionate Thumb 22.9%


  logl

Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.

Contact:

The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.