QuartataWeb 1.0

2 known interactions (targets) of input drug (DB09214): Dexketoprofen

No.	Gene	UniProt ID	Protein Name	Pathway	PDB
1	PTGS1	P23219	Prostaglandin G/H synthase 1	hsa00590; hsa01100; hsa04611; hsa04726; hsa04923	NA
2	PTGS2	P35354	Prostaglandin G/H synthase 2	hsa00590; hsa01100; hsa04064; hsa04370; hsa04625; hsa04657; hsa04668; hsa04723; hsa04726; hsa04913; hsa04921; hsa04923; hsa05140; hsa05163; hsa05165; hsa05167; hsa05200; hsa05204; hsa05206; hsa05222	1V0X

20 predicted interactions (targets) of input drug (DB09214): Dexketoprofen

No.	Gene	UniProt ID	Protein Name	Pathway	PDB	Confidence score
1	ESR1	P03372	Estrogen receptor	hsa01522; hsa04915; hsa04917; hsa04919; hsa04961; hsa05200; hsa05205; hsa05224	1A52; 1AKF; 1ERE; 1ERR; 1G50; 1GWQ; 1GWR; 1HCP; 1HCQ; 1L2I; 1PCG; 1QKT; 1QKU; 1R5K; 1SJ0; 1UOM; 1X7E; 1X7R; 1XP1; 1XP6; 1XP9; 1XPC; 1XQC; 1YIM; 1YIN; 1ZKY; 2AYR; 2B1V; 2B1Z; 2B23; 2BJ4; 2FAI; 2G44; 2G5O; 2I0J; 2IOG; 2IOK; 2JF9; 2JFA; 2LLO; 2LLQ; 2OCF; 2OUZ; 2P15; 2POG; 2Q6J; 2Q70; 2QA6; 2QA8; 2QAB; 2QE4; 2QGT; 2QGW; 2QH6; 2QR9; 2QSE; 2QXM; 2QXS; 2QZO; 2R6W; 2R6Y; 2YAT; 2YJA; 3CBM; 3CBO; 3CBP; 3DT3; 3ERD; 3ERT; 3HLV; 3HM1; 3L03; 3OS8; 3OS9; 3OSA; 3Q95; 3Q97; 3UU7; 3UUA; 3UUC; 3UUD; 4AA6; 4DMA; 4IU7; 4IUI; 4IV2; 4IV4; 4IVW; 4IVY; 4IW6; 4IW8; 4IWC; 4IWF; 4JC3; 4JDD; 4MG5; 4MG6; 4MG7; 4MG8; 4MG9; 4MGA; 4MGB; 4MGC; 4MGD; 4O6F; 4PP6; 4PPP; 4PPS; 4PXM; 4Q13; 4Q50; 4TUZ; 4TV1; 4ZN9; 5AAU; 5AAV; 5AK2	20.0%
2	PLA2G1B	P04054	Phospholipase A2	hsa00564; hsa00565; hsa00590; hsa00591; hsa00592; hsa01100; hsa04014; hsa04270; hsa04972; hsa04975	1YSK; 3ELO	19.9%
3	FBP1	P09467	Fructose-1,6-bisphosphatase 1	hsa00010; hsa00030; hsa00051; hsa01100; hsa01200; hsa04152; hsa04910; hsa04922	1FTA; 2FHY; 2FIE; 2FIX; 2JJK; 2VT5; 2WBB; 2WBD; 2Y5K; 2Y5L; 3A29; 3KBZ; 3KC0; 3KC1; 4MJO	19.3%
4	ALOX5	P09917	Arachidonate 5-lipoxygenase	hsa00590; hsa01100; hsa04664; hsa04726; hsa04913; hsa05145	2ABV; 3O8Y; 3V92; 3V98; 3V99	18.0%
5	SLC12A1	Q13621	Solute carrier family 12 member 1	NA	NA	17.4%
6	TYMS	P04818	Thymidylate synthase	hsa00240; hsa00670; hsa01100; hsa01523	1HVY; 1HW3; 1HW4; 1HZW; 1I00; 1JU6; 1JUJ; 1YPV; 2ONB; 2RD8; 2RDA; 3EAW; 3EBU; 3ED7; 3EDW; 3EF9; 3EGY; 3EHI; 3EJL; 3GG5; 3GH0; 3GH2; 3H9K; 3HB8; 3N5E; 3N5G; 3OB7; 4E28; 4FGT; 4G2O; 4G6W; 4GD7; 4GYH; 4H1I; 4JEF; 4KPW; 4O1U; 4O1X; 4UP1	16.9%
7	CHUK	O15111	Inhibitor of nuclear factor kappa-B kinase subunit alpha	hsa01523; hsa04010; hsa04014; hsa04062; hsa04064; hsa04068; hsa04150; hsa04151; hsa04210; hsa04380; hsa04620; hsa04621; hsa04622; hsa04623; hsa04625; hsa04657; hsa04658; hsa04659; hsa04660; hsa04662; hsa04668; hsa04920; hsa05120; hsa05131; hsa05142; hsa05145; hsa05160; hsa05161; hsa05162; hsa05163; hsa05165; hsa05166; hsa05167; hsa05168; hsa05169; hsa05170; hsa05200; hsa05212; hsa05215; hsa05220; hsa05221; hsa05222; hsa05418	3BRT	16.7%
8	RXRA	P19793	Retinoic acid receptor RXR-alpha	hsa03320; hsa04151; hsa04659; hsa04919; hsa04920; hsa04928; hsa04932; hsa04976; hsa05160; hsa05200; hsa05202; hsa05216; hsa05222; hsa05223; hsa05226	1BY4; 1DSZ; 1FBY; 1FM6; 1FM9; 1G1U; 1G5Y; 1K74; 1LBD; 1MV9; 1MVC; 1MZN; 1R0N; 1RDT; 1RXR; 1XLS; 1XV9; 1XVP; 1YNW; 2ACL; 2NLL; 2P1T; 2P1U; 2P1V; 2ZXZ; 2ZY0; 3DZU; 3DZY; 3E00; 3E94; 3FAL; 3FC6; 3FUG; 3H0A; 3KWY; 3NSP; 3NSQ; 3OAP; 3OZJ; 3PCU; 3R29; 3R2A; 3R5M; 3UVV; 4CN2; 4CN3; 4CN5; 4CN7; 4J5W; 4J5X; 4K4J; 4K6I; 4M8E; 4M8H; 4N5G; 4N8R; 4NQA; 4OC7; 4POH; 4POJ; 4PP3; 4PP5; 4RFW; 4RMC; 4RMD; 4RME; 4ZO1	16.2%
9	APP	P05067	Amyloid beta A4 protein	hsa04726; hsa05010	1AAP; 1AMB; 1AMC; 1AML; 1BA4; 1BA6; 1BJB; 1BJC; 1BRC; 1CA0; 1HZ3; 1IYT; 1MWP; 1OWT; 1QCM; 1QWP; 1QXC; 1QYT; 1TAW; 1TKN; 1UO7; 1UO8; 1UOA; 1UOI; 1X11; 1Z0Q; 1ZE7; 1ZE9; 1ZJD; 2BEG; 2BOM; 2BP4; 2FJZ; 2FK1; 2FK2; 2FK3; 2FKL; 2FMA; 2G47; 2IPU; 2LFM; 2LLM; 2LMN; 2LMO; 2LMP; 2LMQ; 2LNQ; 2LOH; 2LP1; 2LZ3; 2LZ4; 2M4J; 2M9R; 2M9S; 2MGT; 2MJ1; 2MPZ; 2MVX; 2MXU; 2OTK; 2R0W; 2WK3; 2Y29; 2Y2A; 2Y3J; 2Y3K; 2Y3L; 3AYU; 3BAE; 3BKJ; 3DXC; 3DXD; 3DXE; 3GCI; 3IFL; 3IFN; 3IFO; 3IFP; 3JQ5; 3JQL; 3JTI; 3KTM; 3L33; 3L81; 3MOQ; 3MXC; 3MXY; 3NYJ; 3NYL; 3OVJ; 3OW9; 3SV1; 3U0T; 3UMH; 3UMI; 3UMK; 4HIX; 4JFN; 4M1C; 4MDR; 4MVI; 4MVK; 4MVL; 4NGE; 4OJF; 4ONF; 4ONG; 4PQD; 4PWQ; 4XXD; 5AEF; 5CSZ	13.3%
10	ROCK2	O75116	Rho-associated protein kinase 2	hsa04022; hsa04024; hsa04062; hsa04071; hsa04270; hsa04310; hsa04360; hsa04510; hsa04530; hsa04611; hsa04670; hsa04810; hsa04921; hsa05130; hsa05131; hsa05132; hsa05163; hsa05200; hsa05205	4L6Q; 4WOT	12.7%
11	TNFSF11	O14788	Tumor necrosis factor ligand superfamily member 11	hsa04060; hsa04064; hsa04380; hsa04917; hsa04928; hsa05224; hsa05323	3URF; 5BNQ	12.3%
12	NR1I2	O75469	Nuclear receptor subfamily 1 group I member 2	NA	1ILG; 1ILH; 1M13; 1NRL; 1SKX; 2O9I; 2QNV; 3CTB; 3HVL; 3R8D; 4J5W; 4J5X; 4NY9; 4S0S; 4S0T; 4X1F; 4X1G; 4XAO; 4XHD; 5A86	12.3%
13	BACE1	P56817	Beta-secretase 1	hsa05010	1FKN; 1M4H; 1PY1; 1SGZ; 1TQF; 1UJJ; 1UJK; 1W50; 1W51; 1XN2; 1XN3; 1XS7; 1YM2; 1YM4; 2B8L; 2B8V; 2F3E; 2F3F; 2FDP; 2G94; 2HIZ; 2HM1; 2IQG; 2IRZ; 2IS0; 2NTR; 2OAH; 2OF0; 2OHK; 2OHL; 2OHM; 2OHN; 2OHP; 2OHQ; 2OHR; 2OHS; 2OHT; 2OHU; 2P4J; 2P83; 2P8H; 2PH6; 2PH8; 2Q11; 2Q15; 2QK5; 2QMD; 2QMF; 2QMG; 2QP8; 2QU2; 2QU3; 2QZK; 2QZL; 2VA5; 2VA6; 2VA7; 2VIE; 2VIJ; 2VIY; 2VIZ; 2VJ6; 2VJ7; 2VJ9; 2VKM; 2VNM; 2VNN; 2WEZ; 2WF0; 2WF1; 2WF2; 2WF3; 2WF4; 2WJO; 2XFI; 2XFJ; 2XFK; 2ZDZ; 2ZE1; 2ZHR; 2ZHS; 2ZHT; 2ZHU; 2ZHV; 2ZJH; 2ZJI; 2ZJJ; 2ZJK; 2ZJL; 2ZJM; 2ZJN; 3BRA; 3BUF; 3BUG; 3BUH; 3CIB; 3CIC; 3CID; 3CKP; 3CKR; 3DM6; 3DUY; 3DV1; 3DV5; 3EXO; 3FKT; 3H0B; 3HVG; 3HW1; 3I25; 3IGB; 3IN3; 3IN4; 3IND; 3INE; 3INF; 3INH; 3IVH; 3IVI; 3IXJ; 3IXK; 3K5C; 3K5D; 3K5F; 3K5G; 3KMX; 3KMY; 3KN0; 3KYR; 3L38; 3L3A; 3L58; 3L59; 3L5B; 3L5C; 3L5D; 3L5E; 3L5F; 3LHG; 3LNK; 3LPI; 3LPJ; 3LPK; 3MSJ; 3MSK; 3MSL; 3N4L; 3NSH; 3OHF; 3OHH; 3OOZ; 3PI5; 3QBH; 3QI1; 3R1G; 3R2F; 3RSV; 3RSX; 3RTH; 3RTM; 3RTN; 3RU1; 3RVI; 3S2O; 3S7L; 3S7M; 3SKF; 3SKG; 3TPJ; 3TPL; 3TPP; 3TPR; 3U6A; 3UDH; 3UDJ; 3UDK; 3UDM; 3UDN; 3UDP; 3UDQ; 3UDR; 3UDY; 3UFL; 3UQP; 3UQR; 3UQU; 3UQW; 3UQX; 3VEU; 3VF3; 3VG1; 3VV6; 3VV7; 3VV8; 3WB4; 3WB5; 3ZMG; 3ZOV; 4ACU; 4ACX; 4AZY; 4B00; 4B05; 4B0Q; 4B1C; 4B1D; 4B1E; 4B70; 4B72; 4B77; 4B78; 4BEK; 4BFD; 4D83; 4D85; 4D88; 4D89; 4D8C; 4DH6; 4DI2; 4DJU; 4DJV; 4DJW; 4DJX; 4DJY; 4DPF; 4DPI; 4DUS; 4DV9; 4DVF; 4EWO; 4EXG; 4FCO; 4FGX; 4FM7; 4FM8; 4FRI; 4FRJ; 4FRK; 4FRS; 4FS4; 4FSE; 4FSL; 4GID; 4GMI; 4H1E; 4H3F; 4H3G; 4H3I; 4H3J; 4HA5; 4HZT; 4I0D; 4I0E; 4I0F; 4I0G; 4I0H; 4I0I; 4I0J; 4I0Z; 4I10; 4I11; 4I12; 4I1C; 4IVS; 4IVT; 4J0P; 4J0T; 4J0V; 4J0Y; 4J0Z; 4J17; 4J1C; 4J1E; 4J1F; 4J1H; 4J1I; 4J1K; 4JOO; 4JP9; 4JPC; 4JPE; 4K8S; 4K9H; 4KE0; 4KE1; 4L7G; 4L7H; 4L7J; 4LC7; 4LXA; 4LXK; 4LXM; 4N00; 4PZW; 4PZX; 4R5N; 4R8Y; 4R91; 4R92; 4R93; 4R95; 4RCD; 4RCE; 4RCF; 4RRN; 4RRO; 4RRS; 4TRW; 4TRY; 4TRZ; 4WTU; 4WY1; 4WY6; 4X2L; 4X7I; 4XKX; 4XXS; 4YBI; 4ZPE; 4ZPF; 4ZPG; 4ZSM; 4ZSP; 4ZSQ; 4ZSR; 5CLM	12.3%
14	AHR	P35869	Aryl hydrocarbon receptor	hsa04659; hsa04934	NA	12.2%
15	MTNR1B	P49286	Melatonin receptor type 1B	hsa04080; hsa04713	NA	12.0%
16	CYP1B1	Q16678	Cytochrome P450 1B1	hsa00140; hsa00380; hsa00980; hsa04913; hsa05204; hsa05206	3PM0	12.0%
17	AKR1C3	P42330	Aldo-keto reductase family 1 member C3	hsa00140; hsa00590; hsa00790; hsa01100; hsa04913	1RY0; 1RY8; 1S1P; 1S1R; 1S2A; 1S2C; 1XF0; 1ZQ5; 2F38; 2FGB; 3R43; 3R58; 3R6I; 3R7M; 3R8G; 3R8H; 3R94; 3UFY; 3UG8; 3UGR; 3UWE; 4DBS; 4DBU; 4DBW; 4DZ5; 4FA3; 4FAL; 4FAM; 4H7C; 4HMN; 4WDT; 4WDU; 4WDW; 4WDX; 4WRH; 4XVD; 4XVE	11.8%
18	ESR2	Q92731	Estrogen receptor beta	hsa01522; hsa04915; hsa04917; hsa05200; hsa05224	1L2J; 1NDE; 1QKM; 1U3Q; 1U3R; 1U3S; 1U9E; 1X76; 1X78; 1X7B; 1X7J; 1YY4; 1YYE; 1ZAF; 2FSZ; 2GIU; 2I0G; 2JJ3; 2NV7; 2QTU; 2YJD; 2YLY; 2Z4B; 3OLL; 3OLS; 3OMO; 3OMP; 3OMQ; 4J24; 4J26	11.7%
19	CRBN	Q96SW2	Protein cereblon	NA	4M91; 4TZ4	11.7%
20	CLCNKA	P51800	Chloride channel protein ClC-Ka	NA	2PFI	11.6%