QuartataWeb 1.0

3 known interactions (targets) of input drug (DB04930): Permethrin

No.	Gene	UniProt ID	Protein Name	Pathway	PDB
1	ESR1	P03372	Estrogen receptor	hsa01522; hsa04915; hsa04917; hsa04919; hsa04961; hsa05200; hsa05205; hsa05224	1A52; 1AKF; 1ERE; 1ERR; 1G50; 1GWQ; 1GWR; 1HCP; 1HCQ; 1L2I; 1PCG; 1QKT; 1QKU; 1R5K; 1SJ0; 1UOM; 1X7E; 1X7R; 1XP1; 1XP6; 1XP9; 1XPC; 1XQC; 1YIM; 1YIN; 1ZKY; 2AYR; 2B1V; 2B1Z; 2B23; 2BJ4; 2FAI; 2G44; 2G5O; 2I0J; 2IOG; 2IOK; 2JF9; 2JFA; 2LLO; 2LLQ; 2OCF; 2OUZ; 2P15; 2POG; 2Q6J; 2Q70; 2QA6; 2QA8; 2QAB; 2QE4; 2QGT; 2QGW; 2QH6; 2QR9; 2QSE; 2QXM; 2QXS; 2QZO; 2R6W; 2R6Y; 2YAT; 2YJA; 3CBM; 3CBO; 3CBP; 3DT3; 3ERD; 3ERT; 3HLV; 3HM1; 3L03; 3OS8; 3OS9; 3OSA; 3Q95; 3Q97; 3UU7; 3UUA; 3UUC; 3UUD; 4AA6; 4DMA; 4IU7; 4IUI; 4IV2; 4IV4; 4IVW; 4IVY; 4IW6; 4IW8; 4IWC; 4IWF; 4JC3; 4JDD; 4MG5; 4MG6; 4MG7; 4MG8; 4MG9; 4MGA; 4MGB; 4MGC; 4MGD; 4O6F; 4PP6; 4PPP; 4PPS; 4PXM; 4Q13; 4Q50; 4TUZ; 4TV1; 4ZN9; 5AAU; 5AAV; 5AK2
2	NR1I2	O75469	Nuclear receptor subfamily 1 group I member 2	NA	1ILG; 1ILH; 1M13; 1NRL; 1SKX; 2O9I; 2QNV; 3CTB; 3HVL; 3R8D; 4J5W; 4J5X; 4NY9; 4S0S; 4S0T; 4X1F; 4X1G; 4XAO; 4XHD; 5A86
3	SCN1A	P35498	Sodium channel protein type 1 subunit alpha	hsa04728	NA

20 predicted interactions (targets) of input drug (DB04930): Permethrin

No.	Gene	UniProt ID	Protein Name	Pathway	PDB	Confidence score
1	ESR2	Q92731	Estrogen receptor beta	hsa01522; hsa04915; hsa04917; hsa05200; hsa05224	1L2J; 1NDE; 1QKM; 1U3Q; 1U3R; 1U3S; 1U9E; 1X76; 1X78; 1X7B; 1X7J; 1YY4; 1YYE; 1ZAF; 2FSZ; 2GIU; 2I0G; 2JJ3; 2NV7; 2QTU; 2YJD; 2YLY; 2Z4B; 3OLL; 3OLS; 3OMO; 3OMP; 3OMQ; 4J24; 4J26	46.1%
2	SHBG	P04278	Sex hormone-binding globulin	NA	1D2S; 1F5F; 1KDK; 1KDM; 1LHN; 1LHO; 1LHU; 1LHV; 1LHW	39.7%
3	NCOA2	Q15596	Nuclear receptor coactivator 2	hsa04915; hsa04919	1GWQ; 1GWR; 1M2Z; 1MV9; 1MVC; 1MZN; 1P93; 1T63; 1T65; 1UHL; 1YOK; 1ZDT; 1ZDU; 1ZKY; 2AO6; 2B1V; 2B1Z; 2B23; 2FAI; 2G44; 2G5O; 2LDC; 2P15; 2P1T; 2P1U; 2P1V; 2Q7J; 2Q7L; 2YJD; 2ZXZ; 2ZY0; 3A9E; 3CLD; 3DZU; 3DZY; 3E00; 3E7C; 3E94; 3ERD; 3FUG; 3GN8; 3K22; 3K23; 3KWY; 3KYT; 3L0E; 3L0J; 3L0L; 3O1D; 3O1E; 3OAP; 3OZJ; 3PCU; 3PLZ; 3Q95; 3Q97; 3R5M; 3UP0; 3UP3; 4CSJ; 4DOS; 4E2J; 4FHH; 4FHI; 4IA1; 4IA2; 4IA3; 4IA7; 4IQR; 4IU7; 4IUI; 4IV2; 4IV4; 4IVW; 4IVY; 4IW6; 4IW8; 4IWC; 4IWF; 4K4J; 4K6I; 4M8E; 4M8H; 4NIE; 4NQA; 4OC7; 4P6W; 4P6X; 4POH; 4POJ; 4PP3; 4PP5; 4PP6; 4PPP; 4PPS; 4PXM; 4Q0A; 4QE6; 4QE8; 4RFW; 4RMC; 4RMD; 4RME; 4RUO; 4WG0; 4ZN9; 4ZO1	36.7%
4	PGR	P06401	Progesterone receptor	hsa04114; hsa04914; hsa04915; hsa05224	1A28; 1E3K; 1SQN; 1SR7; 1ZUC; 2C7A; 2OVH; 2OVM; 2W8Y; 3D90; 3G8O; 3HQ5; 3KBA; 3ZR7; 3ZRA; 3ZRB; 4A2J; 4APU; 4OAR	34.7%
5	SCN3A	Q9NY46	Sodium channel protein type 3 subunit alpha	hsa04742	NA	31.4%
6	SCN5A	Q14524	Sodium channel protein type 5 subunit alpha	hsa04261	2KBI; 2L53; 4DCK; 4DJC; 4JQ0; 4OVN	31.1%
7	AR	P10275	Androgen receptor	hsa04114; hsa05200; hsa05215	1E3G; 1GS4; 1T5Z; 1T63; 1T65; 1XJ7; 1XOW; 1XQ3; 1Z95; 2AM9; 2AMA; 2AMB; 2AO6; 2AX6; 2AX7; 2AX8; 2AX9; 2AXA; 2HVC; 2OZ7; 2PIO; 2PIP; 2PIQ; 2PIR; 2PIT; 2PIU; 2PIV; 2PIW; 2PIX; 2PKL; 2PNU; 2Q7I; 2Q7J; 2Q7K; 2Q7L; 2YHD; 2YLO; 2YLP; 2YLQ; 2Z4J; 3B5R; 3B65; 3B66; 3B67; 3B68; 3BTR; 3L3X; 3L3Z; 3RLJ; 3RLL; 3V49; 3V4A; 3ZQT; 4HLW; 4K7A; 4OEA; 4OED; 4OEY; 4OEZ; 4OFR; 4OFU; 4OGH; 4OH5; 4OH6; 4OHA; 4OIL; 4OIU; 4OJ9; 4OJB; 4OK1; 4OKB; 4OKT; 4OKW; 4OKX; 4OLM; 4QL8; 4U4K	28.0%
8	ESRRG	P62508	Estrogen-related receptor gamma	NA	1KV6; 1TFC; 1VJB; 2E2R; 2EWP; 2GP7; 2GPO; 2GPP; 2GPU; 2GPV; 2P7A; 2P7G; 2P7Z; 2ZAS; 2ZBS; 2ZKC	26.7%
9	SCN2A	Q99250	Sodium channel protein type 2 subunit alpha	hsa04742	2KAV; 4JPZ	24.9%
10	BECN1	Q14457	Beclin-1	hsa04136; hsa04137; hsa04140; hsa04215; hsa04371; hsa05167	2P1L; 2PON; 3DVU; 4DDP; 4MI8; 5EFM; 5HHE	24.5%
11	HSD17B2	P37059	Estradiol 17-beta-dehydrogenase 2	hsa00140; hsa01100; hsa04913	NA	24.0%
12	MT-ATP6	P00846	ATP synthase subunit a	hsa00190; hsa01100; hsa04714; hsa05010; hsa05012; hsa05016	NA	23.4%
13	CHRNA4	P43681	Neuronal acetylcholine receptor subunit alpha-4	hsa04080; hsa04725; hsa05033	2GVT; 2LLY	22.9%
14	SCN10A	Q9Y5Y9	Sodium channel protein type 10 subunit alpha	NA	NA	22.8%
15	SCN1B	Q07699	Sodium channel subunit beta-1	hsa04261	NA	22.1%
16	PPARA	Q07869	Peroxisome proliferator-activated receptor alpha	hsa03320; hsa04024; hsa04920; hsa04922; hsa04931; hsa04932; hsa05160	1I7G; 1K7L; 1KKQ; 2NPA; 2P54; 2REW; 2ZNN; 3ET1; 3FEI; 3G8I; 3KDT; 3KDU; 3SP6; 3VI8; 4BCR; 4CI4	21.9%
17	CDK2	P24941	Cyclin-dependent kinase 2	hsa04068; hsa04110; hsa04114; hsa04115; hsa04151; hsa04218; hsa04914; hsa04934; hsa05161; hsa05162; hsa05165; hsa05168; hsa05169; hsa05200; hsa05203; hsa05215; hsa05222; hsa05226	1AQ1; 1B38; 1B39; 1BUH; 1CKP; 1DI8; 1DM2; 1E1V; 1E1X; 1E9H; 1F5Q; 1FIN; 1FQ1; 1FVT; 1FVV; 1G5S; 1GIH; 1GII; 1GIJ; 1GY3; 1GZ8; 1H00; 1H01; 1H07; 1H08; 1H0V; 1H0W; 1H1P; 1H1Q; 1H1R; 1H1S; 1H24; 1H25; 1H26; 1H27; 1H28; 1HCK; 1HCL; 1JST; 1JSU; 1JSV; 1JVP; 1KE5; 1KE6; 1KE7; 1KE8; 1KE9; 1OGU; 1OI9; 1OIQ; 1OIR; 1OIT; 1OIU; 1OIY; 1OKV; 1OKW; 1OL1; 1OL2; 1P2A; 1P5E; 1PF8; 1PKD; 1PW2; 1PXI; 1PXJ; 1PXK; 1PXL; 1PXM; 1PXN; 1PXO; 1PXP; 1PYE; 1QMZ; 1R78; 1URC; 1URW; 1V1K; 1VYW; 1VYZ; 1W0X; 1W8C; 1W98; 1WCC; 1Y8Y; 1Y91; 1YKR; 2A0C; 2A4L; 2B52; 2B53; 2B54; 2B55; 2BHE; 2BHH; 2BKZ; 2BPM; 2BTR; 2BTS; 2C4G; 2C5N; 2C5O; 2C5V; 2C5X; 2C5Y; 2C68; 2C69; 2C6I; 2C6K; 2C6L; 2C6M; 2C6O; 2C6T; 2CCH; 2CCI; 2CJM; 2CLX; 2DS1; 2DUV; 2EXM; 2FVD; 2G9X; 2HIC; 2I40; 2IW6; 2IW8; 2IW9; 2J9M; 2JGZ; 2R3F; 2R3G; 2R3H; 2R3I; 2R3J; 2R3K; 2R3L; 2R3M; 2R3N; 2R3O; 2R3P; 2R3Q; 2R3R; 2R64; 2UUE; 2UZB; 2UZD; 2UZE; 2UZL; 2UZN; 2UZO; 2V0D; 2V22; 2VTA; 2VTH; 2VTI; 2VTJ; 2VTL; 2VTM; 2VTN; 2VTO; 2VTP; 2VTQ; 2VTR; 2VTS; 2VTT; 2VU3; 2VV9; 2W05; 2W06; 2W17; 2W1H; 2WEV; 2WFY; 2WHB; 2WIH; 2WIP; 2WMA; 2WMB; 2WPA; 2WXV; 2X1N; 2XMY; 2XNB; 3BHT; 3BHU; 3BHV; 3DDP; 3DDQ; 3DOG; 3EID; 3EJ1; 3EOC; 3EZR; 3EZV; 3F5X; 3FZ1; 3IG7; 3IGG; 3LE6; 3LFN; 3LFQ; 3LFS; 3MY5; 3NS9; 3PJ8; 3PXF; 3PXQ; 3PXR; 3PXY; 3PXZ; 3PY0; 3PY1; 3QHR; 3QHW; 3QL8; 3QQF; 3QQG; 3QQH; 3QQJ; 3QQK; 3QQL; 3QRT; 3QRU; 3QTQ; 3QTR; 3QTS; 3QTU; 3QTW; 3QTX; 3QTZ; 3QU0; 3QWJ; 3QWK; 3QX2; 3QX4; 3QXO; 3QXP; 3QZF; 3QZG; 3QZH; 3QZI; 3R1Q; 3R1S; 3R1Y; 3R28; 3R6X; 3R71; 3R73; 3R7E; 3R7I; 3R7U; 3R7V; 3R7Y; 3R83; 3R8L; 3R8M; 3R8P; 3R8U; 3R8V; 3R8Z; 3R9D; 3R9H; 3R9N; 3R9O; 3RAH; 3RAI; 3RAK; 3RAL; 3RJC; 3RK5; 3RK7; 3RK9; 3RKB; 3RM6; 3RM7; 3RMF; 3RNI; 3ROY; 3RPO; 3RPR; 3RPV; 3RPY; 3RZB; 3S00; 3S0O; 3S1H; 3S2P; 3SQQ; 3SW4; 3SW7; 3TI1; 3TIY; 3TIZ; 3TNW; 3ULI; 3UNJ; 3UNK; 3WBL; 4ACM; 4BCK; 4BCM; 4BCN; 4BCO; 4BCP; 4BCQ; 4BGH; 4BZD; 4CFM; 4CFN; 4CFU; 4CFV; 4CFW; 4CFX; 4D1X; 4D1Z; 4EK3; 4EK4; 4EK5; 4EK6; 4EK8; 4EOI; 4EOJ; 4EOK; 4EOL; 4EOM; 4EON; 4EOO; 4EOP; 4EOQ; 4EOR; 4EOS; 4ERW; 4EZ3; 4EZ7; 4FKG; 4FKI; 4FKJ; 4FKL; 4FKO; 4FKP; 4FKQ; 4FKR; 4FKS; 4FKT; 4FKU; 4FKV; 4FKW; 4FX3; 4GCJ; 4I3Z; 4II5; 4KD1; 4LYN; 4NJ3; 4RJ3; 5A14; 5CYI; 5D1J	21.3%
18	ESRRA	P11474	Steroid hormone receptor ERR1	NA	1XB7; 2PJL; 3D24; 3K6P	21.3%
19	CACNA1I	Q9P0X4	Voltage-dependent T-type calcium channel subunit alpha-1I	hsa04010; hsa04020; hsa04713; hsa04925; hsa04927; hsa04934	NA	21.1%
20	GABRB1	P18505	Gamma-aminobutyric acid receptor subunit beta-1	hsa04080; hsa04723; hsa04726; hsa04727; hsa05032; hsa05033	NA	20.8%