QuartataWeb 1.0

1 known interactions (targets) of input drug (DB04689): 2-{5-[3-(6-BENZOYL-1-PROPYLNAPHTHALEN-2-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID

No.	Gene	UniProt ID	Protein Name	Pathway	PDB
1	PPARG	P37231	Peroxisome proliferator-activated receptor gamma	hsa03320; hsa04152; hsa04211; hsa04380; hsa04714; hsa05016; hsa05200; hsa05202; hsa05216	1FM6; 1FM9; 1I7I; 1K74; 1KNU; 1NYX; 1PRG; 1RDT; 1WM0; 1ZEO; 1ZGY; 2ATH; 2F4B; 2FVJ; 2G0G; 2G0H; 2GTK; 2HFP; 2HWQ; 2HWR; 2I4J; 2I4P; 2I4Z; 2OM9; 2P4Y; 2POB; 2PRG; 2Q59; 2Q5P; 2Q5S; 2Q61; 2Q6R; 2Q6S; 2Q8S; 2QMV; 2VSR; 2VST; 2VV0; 2VV1; 2VV2; 2VV3; 2VV4; 2XKW; 2YFE; 2ZK0; 2ZK1; 2ZK2; 2ZK3; 2ZK4; 2ZK5; 2ZK6; 2ZNO; 2ZVT; 3ADS; 3ADT; 3ADU; 3ADV; 3ADW; 3ADX; 3AN3; 3AN4; 3B0Q; 3B0R; 3B1M; 3B3K; 3BC5; 3CDP; 3CDS; 3CS8; 3CWD; 3D6D; 3DZU; 3DZY; 3E00; 3ET0; 3ET3; 3FEJ; 3FUR; 3G9E; 3GBK; 3H0A; 3HO0; 3HOD; 3IA6; 3K8S; 3KMG; 3LMP; 3NOA; 3OSI; 3OSW; 3PBA; 3PO9; 3PRG; 3QT0; 3R5N; 3R8A; 3R8I; 3S9S; 3SZ1; 3T03; 3TY0; 3U9Q; 3V9T; 3V9V; 3V9Y; 3VJH; 3VJI; 3VN2; 3VSO; 3VSP; 3WJ4; 3WJ5; 3WMH; 3X1H; 3X1I; 4A4V; 4A4W; 4CI5; 4E4K; 4E4Q; 4EM9; 4EMA; 4F9M; 4FGY; 4HEE; 4JAZ; 4JL4; 4L96; 4L98; 4O8F; 4OJ4; 4PRG; 4PVU; 4PWL; 4R2U; 4R6S; 4XLD; 4XTA; 4XUM; 4Y29

20 predicted interactions (targets) of input drug (DB04689): 2-{5-[3-(6-BENZOYL-1-PROPYLNAPHTHALEN-2-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID

No.	Gene	UniProt ID	Protein Name	Pathway	PDB	Confidence score
1	PPARA	Q07869	Peroxisome proliferator-activated receptor alpha	hsa03320; hsa04024; hsa04920; hsa04922; hsa04931; hsa04932; hsa05160	1I7G; 1K7L; 1KKQ; 2NPA; 2P54; 2REW; 2ZNN; 3ET1; 3FEI; 3G8I; 3KDT; 3KDU; 3SP6; 3VI8; 4BCR; 4CI4	37.5%
2	PPARD	Q03181	Peroxisome proliferator-activated receptor delta	hsa03320; hsa04310; hsa05200; hsa05221	1GWX; 1Y0S; 2AWH; 2B50; 2BAW; 2ENV; 2GWX; 2J14; 2Q5G; 2XYJ; 2XYW; 2XYX; 2ZNP; 2ZNQ; 3D5F; 3DY6; 3ET2; 3GWX; 3GZ9; 3OZ0; 3PEQ; 3SP9; 3TKM	29.2%
3	PLG	P00747	Plasminogen	hsa04080; hsa04610; hsa05150; hsa05164	1B2I; 1BML; 1BUI; 1CEA; 1CEB; 1DDJ; 1HPJ; 1HPK; 1I5K; 1KI0; 1KRN; 1L4D; 1L4Z; 1PK4; 1PKR; 1PMK; 1QRZ; 1RJX; 2DOH; 2DOI; 2KNF; 2L0S; 2PK4; 3UIR; 4A5T; 4CIK; 4DCB; 4DUR; 4DUU; 5HPG	16.2%
4	SERPINE1	P05121	Plasminogen activator inhibitor 1	hsa04066; hsa04115; hsa04218; hsa04371; hsa04390; hsa04610; hsa04933; hsa05142	1A7C; 1B3K; 1C5G; 1DB2; 1DVM; 1DVN; 1LJ5; 1OC0; 3CVM; 3EOX; 3PB1; 3Q02; 3Q03; 3R4L; 3UT3; 4AQH; 4G8O; 4G8R; 4IC0; 5BRR; 9PAI	15.9%
5	LTA4H	P09960	Leukotriene A-4 hydrolase	hsa00590; hsa01100	1GW6; 1H19; 1HS6; 1SQM; 2R59; 2VJ8; 3B7R; 3B7S; 3B7T; 3B7U; 3CHO; 3CHP; 3CHQ; 3CHR; 3CHS; 3FH5; 3FH7; 3FH8; 3FHE; 3FTS; 3FTU; 3FTV; 3FTW; 3FTX; 3FTY; 3FTZ; 3FU0; 3FU3; 3FU5; 3FU6; 3FUD; 3FUE; 3FUF; 3FUH; 3FUI; 3FUJ; 3FUK; 3FUL; 3FUM; 3FUN; 3U9W; 4DPR; 4L2L; 4MKT; 4MS6; 5AEN	15.4%
6	AR	P10275	Androgen receptor	hsa04114; hsa05200; hsa05215	1E3G; 1GS4; 1T5Z; 1T63; 1T65; 1XJ7; 1XOW; 1XQ3; 1Z95; 2AM9; 2AMA; 2AMB; 2AO6; 2AX6; 2AX7; 2AX8; 2AX9; 2AXA; 2HVC; 2OZ7; 2PIO; 2PIP; 2PIQ; 2PIR; 2PIT; 2PIU; 2PIV; 2PIW; 2PIX; 2PKL; 2PNU; 2Q7I; 2Q7J; 2Q7K; 2Q7L; 2YHD; 2YLO; 2YLP; 2YLQ; 2Z4J; 3B5R; 3B65; 3B66; 3B67; 3B68; 3BTR; 3L3X; 3L3Z; 3RLJ; 3RLL; 3V49; 3V4A; 3ZQT; 4HLW; 4K7A; 4OEA; 4OED; 4OEY; 4OEZ; 4OFR; 4OFU; 4OGH; 4OH5; 4OH6; 4OHA; 4OIL; 4OIU; 4OJ9; 4OJB; 4OK1; 4OKB; 4OKT; 4OKW; 4OKX; 4OLM; 4QL8; 4U4K	15.3%
7	NCOA1	Q15788	Nuclear receptor coactivator 1	hsa04915; hsa04919; hsa05200; hsa05224	1FM6; 1FM9; 1K4W; 1K74; 1K7L; 1KV6; 1N4H; 1NQ7; 1NRL; 1P8D; 1PZL; 1RDT; 1TFC; 1U3R; 1U3S; 1X76; 1X78; 1X7B; 1X7J; 1XIU; 1XV9; 1XVP; 1YY4; 1YYE; 1ZAF; 2A3I; 2C52; 2FVJ; 2GTK; 2HBH; 2HC4; 2HCD; 2HFP; 2NPA; 2NV7; 2P54; 2PRG; 3BEJ; 3BQD; 3CTB; 3CWD; 3DCT; 3DCU; 3DR1; 3ET1; 3ET3; 3FEI; 3FEJ; 3FUR; 3FXV; 3G8I; 3G9E; 3GYT; 3GYU; 3H0A; 3HC5; 3HC6; 3HVL; 3IPQ; 3IPS; 3IPU; 3KMR; 3LMP; 3OKH; 3OKI; 3OLF; 3OLL; 3OLS; 3OMK; 3OMM; 3OMO; 3OMP; 3OMQ; 3OOF; 3OOK; 3P88; 3P89; 3QT0; 3RUT; 3RUU; 3RVF; 3S9S; 3T03; 3UU7; 3UUA; 3UUD; 3V9Y; 3VN2; 4DK7; 4DK8; 4DM6; 4DM8; 4DQM; 4F9M; 4FGY; 4G1D; 4G1Y; 4G1Z; 4G20; 4G21; 4G2H; 4HEE; 4J5X; 4JYG; 4JYH; 4JYI; 4MG5; 4MG6; 4MG7; 4MG8; 4MG9; 4MGA; 4MGB; 4MGC; 4MGD; 4RUJ; 4RUP; 4TUZ; 4TV1; 4Y29; 5A86; 5AVI; 5AVL	15.0%
8	PNP	P00491	Purine nucleoside phosphorylase	hsa00230; hsa00240; hsa00760; hsa01100	1M73; 1PF7; 1PWY; 1RCT; 1RFG; 1RR6; 1RSZ; 1RT9; 1ULA; 1ULB; 1V2H; 1V3Q; 1V41; 1V45; 1YRY; 2A0W; 2A0X; 2A0Y; 2OC4; 2OC9; 2ON6; 2Q7O; 3BGS; 3D1V; 3GB9; 3GGS; 3INY; 3K8O; 3K8Q; 3PHB; 4EAR; 4EB8; 4ECE; 4GKA	15.0%
9	ABCC8	Q09428	ATP-binding cassette sub-family C member 8	hsa02010; hsa04911; hsa04930	NA	14.8%
10	mmp20	O43923	Matrix metalloproteinase-25	NA	NA	14.8%
11	GSTP1	P09211	Glutathione S-transferase P	hsa00480; hsa00980; hsa00982; hsa00983; hsa01524; hsa05200; hsa05204; hsa05215; hsa05225; hsa05418	10GS; 11GS; 12GS; 13GS; 14GS; 16GS; 17GS; 18GS; 19GS; 1AQV; 1AQW; 1AQX; 1EOG; 1EOH; 1GSS; 1KBN; 1LBK; 1MD3; 1MD4; 1PGT; 1PX6; 1PX7; 1ZGN; 20GS; 22GS; 2A2R; 2A2S; 2GSS; 2J9H; 2PGT; 3CSH; 3CSI; 3CSJ; 3DD3; 3DGQ; 3GSS; 3GUS; 3HJM; 3HJO; 3HKR; 3IE3; 3KM6; 3KMN; 3KMO; 3N9J; 3PGT; 4GSS; 4PGT; 5GSS; 6GSS; 7GSS; 8GSS; 9GSS	14.1%
12	PLAT	P00750	Tissue-type plasminogen activator	hsa04371; hsa04610; hsa05202; hsa05215; hsa05418	1A5H; 1BDA; 1PK2; 1PML; 1RTF; 1TPG; 1TPK; 1TPM; 1TPN; 5BRR	14.0%
13	PIM1	P11309	Serine/threonine-protein kinase pim-1	hsa04630; hsa04933; hsa05200; hsa05206; hsa05221	1XQZ; 1XR1; 1XWS; 1YHS; 1YI3; 1YI4; 1YWV; 1YXS; 1YXT; 1YXU; 1YXV; 1YXX; 2BIK; 2BIL; 2BZH; 2BZI; 2BZJ; 2BZK; 2C3I; 2J2I; 2O3P; 2O63; 2O64; 2O65; 2OBJ; 2OI4; 2XIX; 2XIY; 2XIZ; 2XJ0; 2XJ1; 2XJ2; 3A99; 3BGP; 3BGQ; 3BGZ; 3BWF; 3C4E; 3CXW; 3CY2; 3CY3; 3DCV; 3F2A; 3JPV; 3JXW; 3JY0; 3JYA; 3MA3; 3QF9; 3R00; 3R01; 3R02; 3R04; 3T9I; 3UIX; 3UMW; 3UMX; 3VBQ; 3VBT; 3VBV; 3VBW; 3VBX; 3VBY; 3VC4; 3WE8; 4A7C; 4ALU; 4ALV; 4ALW; 4AS0; 4BZN; 4BZO; 4DTK; 4ENX; 4ENY; 4GW8; 4I41; 4IAA; 4JX3; 4JX7; 4K0Y; 4K18; 4K1B; 4LL5; 4LM5; 4LMU; 4MBI; 4MBL; 4MED; 4MTA; 4N6Y; 4N6Z; 4N70; 4RBL; 4RC2; 4RC3; 4RC4; 4RPV; 4TY1; 4WRS; 4WSY; 4WT6; 4XH6; 4XHK; 5DGZ; 5DHJ; 5DIA; 5DWR	13.7%
14	NOS1	P29475	Nitric oxide synthase, brain	hsa00220; hsa00330; hsa01100; hsa04020; hsa04145; hsa04371; hsa04713; hsa04730; hsa04926; hsa04970; hsa05010; hsa05014	4D1N; 4UCH; 4UH5; 4UH6; 4V3U; 5ADF; 5ADG; 5ADI	13.4%
15	ACSL4	O60488	Long-chain-fatty-acid--CoA ligase 4	hsa00061; hsa00071; hsa01100; hsa01212; hsa03320; hsa04146; hsa04216; hsa04714; hsa04920	NA	13.3%
16	F2	P00734	Prothrombin	hsa04080; hsa04610; hsa04810	1A2C; 1A3B; 1A3E; 1A46; 1A4W; 1A5G; 1A61; 1ABI; 1ABJ; 1AD8; 1AE8; 1AFE; 1AHT; 1AI8; 1AIX; 1AWF; 1AWH; 1AY6; 1B5G; 1B7X; 1BA8; 1BB0; 1BCU; 1BHX; 1BMM; 1BMN; 1BTH; 1C1U; 1C1V; 1C1W; 1C4U; 1C4V; 1C4Y; 1C5L; 1C5N; 1C5O; 1CA8; 1D3D; 1D3P; 1D3Q; 1D3T; 1D4P; 1D6W; 1D9I; 1DE7; 1DIT; 1DM4; 1DOJ; 1DWB; 1DWC; 1DWD; 1DWE; 1DX5; 1E0F; 1EB1; 1EOJ; 1EOL; 1FPC; 1FPH; 1G30; 1G32; 1G37; 1GHV; 1GHW; 1GHX; 1GHY; 1GJ4; 1GJ5; 1H8D; 1H8I; 1HAG; 1HAH; 1HAI; 1HAO; 1HAP; 1HBT; 1HDT; 1HGT; 1HLT; 1HUT; 1HXE; 1HXF; 1IHS; 1IHT; 1JMO; 1JOU; 1JWT; 1K21; 1K22; 1KTS; 1KTT; 1LHC; 1LHD; 1LHE; 1LHF; 1LHG; 1MH0; 1MU6; 1MU8; 1MUE; 1NM6; 1NO9; 1NRN; 1NRO; 1NRP; 1NRQ; 1NRR; 1NRS; 1NT1; 1NU7; 1NU9; 1NY2; 1NZQ; 1O0D; 1O2G; 1O5G; 1OOK; 1OYT; 1P8V; 1PPB; 1QBV; 1QHR; 1QJ1; 1QJ6; 1QJ7; 1QUR; 1RD3; 1RIW; 1SB1; 1SFQ; 1SG8; 1SGI; 1SHH; 1SL3; 1SR5; 1T4U; 1T4V; 1TA2; 1TA6; 1TB6; 1TBZ; 1THP; 1THR; 1THS; 1TMB; 1TMT; 1TMU; 1TOM; 1TQ0; 1TQ7; 1TWX; 1UMA; 1UVS; 1VR1; 1VZQ; 1W7G; 1WAY; 1WBG; 1XM1; 1XMN; 1YPE; 1YPG; 1YPJ; 1YPK; 1YPL; 1YPM; 1Z71; 1Z8I; 1Z8J; 1ZGI; 1ZGV; 1ZRB; 2A0Q; 2A2X; 2A45; 2AFQ; 2ANK; 2ANM; 2B5T; 2BDY; 2BVR; 2BVS; 2BVX; 2BXT; 2BXU; 2C8W; 2C8X; 2C8Y; 2C8Z; 2C90; 2C93; 2CF8; 2CF9; 2CN0; 2FEQ; 2FES; 2GDE; 2GP9; 2H9T; 2HGT; 2HNT; 2HPP; 2HPQ; 2HWL; 2JH0; 2JH5; 2JH6; 2OD3; 2PGB; 2PGQ; 2PKS; 2PW8; 2R2M; 2THF; 2UUF; 2UUJ; 2UUK; 2V3H; 2V3O; 2ZC9; 2ZDA; 2ZDV; 2ZF0; 2ZFF; 2ZFP; 2ZFQ; 2ZFR; 2ZG0; 2ZGB; 2ZGX; 2ZHE; 2ZHF; 2ZHQ; 2ZHW; 2ZI2; 2ZIQ; 2ZNK; 2ZO3; 3B23; 3B9F; 3BEF; 3BEI; 3BF6; 3BIU; 3BIV; 3BV9; 3C1K; 3C27; 3D49; 3DA9; 3DD2; 3DHK; 3DT0; 3DUX; 3E6P; 3EE0; 3EGK; 3EQ0; 3F68; 3GIC; 3GIS; 3HAT; 3HKJ; 3HTC; 3JZ1; 3JZ2; 3K65; 3LDX; 3LU9; 3NXP; 3P17; 3P6Z; 3P70; 3PMH; 3PO1; 3QDZ; 3QGN; 3QLP; 3QTO; 3QTV; 3QWC; 3QX5; 3R3G; 3RLW; 3RLY; 3RM0; 3RM2; 3RML; 3RMM; 3RMN; 3RMO; 3S7H; 3S7K; 3SHA; 3SHC; 3SI3; 3SI4; 3SQE; 3SQH; 3SV2; 3T5F; 3TU7; 3U69; 3U8O; 3U8R; 3U8T; 3U98; 3U9A; 3UTU; 3UWJ; 3VXE; 3VXF; 4AX9; 4AYV; 4AYY; 4AZ2; 4BAH; 4BAK; 4BAM; 4BAN; 4BAO; 4BAQ; 4BOH; 4CH2; 4CH8; 4DIH; 4DII; 4DT7; 4DY7; 4E05; 4E06; 4E7R; 4H6S; 4H6T; 4HFP; 4HTC; 4HZH; 4I7Y; 4LOY; 4LXB; 4LZ1; 4LZ4; 4MLF; 4N3L; 4NZE; 4NZQ; 4O03; 4RKJ; 4RKO; 4RN6; 4THN; 4UD9; 4UDW; 4UE7; 4UEH; 4YES; 5AF9; 5AFY; 5AFZ; 5AHG; 5E8E; 5GDS; 7KME; 8KME	13.2%
17	AGTR1	P30556	Type-1 angiotensin II receptor	hsa04020; hsa04022; hsa04072; hsa04080; hsa04261; hsa04270; hsa04371; hsa04614; hsa04924; hsa04925; hsa04927; hsa04933; hsa04934; hsa05200	1ZV0; 4YAY; 4ZUD	13.2%
18	APP	P05067	Amyloid beta A4 protein	hsa04726; hsa05010	1AAP; 1AMB; 1AMC; 1AML; 1BA4; 1BA6; 1BJB; 1BJC; 1BRC; 1CA0; 1HZ3; 1IYT; 1MWP; 1OWT; 1QCM; 1QWP; 1QXC; 1QYT; 1TAW; 1TKN; 1UO7; 1UO8; 1UOA; 1UOI; 1X11; 1Z0Q; 1ZE7; 1ZE9; 1ZJD; 2BEG; 2BOM; 2BP4; 2FJZ; 2FK1; 2FK2; 2FK3; 2FKL; 2FMA; 2G47; 2IPU; 2LFM; 2LLM; 2LMN; 2LMO; 2LMP; 2LMQ; 2LNQ; 2LOH; 2LP1; 2LZ3; 2LZ4; 2M4J; 2M9R; 2M9S; 2MGT; 2MJ1; 2MPZ; 2MVX; 2MXU; 2OTK; 2R0W; 2WK3; 2Y29; 2Y2A; 2Y3J; 2Y3K; 2Y3L; 3AYU; 3BAE; 3BKJ; 3DXC; 3DXD; 3DXE; 3GCI; 3IFL; 3IFN; 3IFO; 3IFP; 3JQ5; 3JQL; 3JTI; 3KTM; 3L33; 3L81; 3MOQ; 3MXC; 3MXY; 3NYJ; 3NYL; 3OVJ; 3OW9; 3SV1; 3U0T; 3UMH; 3UMI; 3UMK; 4HIX; 4JFN; 4M1C; 4MDR; 4MVI; 4MVK; 4MVL; 4NGE; 4OJF; 4ONF; 4ONG; 4PQD; 4PWQ; 4XXD; 5AEF; 5CSZ	12.9%
19	TRPV1	Q8NER1	Transient receptor potential cation channel subfamily V member 1	hsa04080; hsa04750	NA	12.8%
20	LCN9	Q8WX39	Epididymal-specific lipocalin-9	NA	NA	12.8%