QuartataWeb 1.0

7 known interactions (targets) of input drug (DB00100): Coagulation Factor IX (Recombinant)

No.	Gene	UniProt ID	Protein Name	Pathway	PDB
1	F2	P00734	Prothrombin	hsa04080; hsa04610; hsa04810	1A2C; 1A3B; 1A3E; 1A46; 1A4W; 1A5G; 1A61; 1ABI; 1ABJ; 1AD8; 1AE8; 1AFE; 1AHT; 1AI8; 1AIX; 1AWF; 1AWH; 1AY6; 1B5G; 1B7X; 1BA8; 1BB0; 1BCU; 1BHX; 1BMM; 1BMN; 1BTH; 1C1U; 1C1V; 1C1W; 1C4U; 1C4V; 1C4Y; 1C5L; 1C5N; 1C5O; 1CA8; 1D3D; 1D3P; 1D3Q; 1D3T; 1D4P; 1D6W; 1D9I; 1DE7; 1DIT; 1DM4; 1DOJ; 1DWB; 1DWC; 1DWD; 1DWE; 1DX5; 1E0F; 1EB1; 1EOJ; 1EOL; 1FPC; 1FPH; 1G30; 1G32; 1G37; 1GHV; 1GHW; 1GHX; 1GHY; 1GJ4; 1GJ5; 1H8D; 1H8I; 1HAG; 1HAH; 1HAI; 1HAO; 1HAP; 1HBT; 1HDT; 1HGT; 1HLT; 1HUT; 1HXE; 1HXF; 1IHS; 1IHT; 1JMO; 1JOU; 1JWT; 1K21; 1K22; 1KTS; 1KTT; 1LHC; 1LHD; 1LHE; 1LHF; 1LHG; 1MH0; 1MU6; 1MU8; 1MUE; 1NM6; 1NO9; 1NRN; 1NRO; 1NRP; 1NRQ; 1NRR; 1NRS; 1NT1; 1NU7; 1NU9; 1NY2; 1NZQ; 1O0D; 1O2G; 1O5G; 1OOK; 1OYT; 1P8V; 1PPB; 1QBV; 1QHR; 1QJ1; 1QJ6; 1QJ7; 1QUR; 1RD3; 1RIW; 1SB1; 1SFQ; 1SG8; 1SGI; 1SHH; 1SL3; 1SR5; 1T4U; 1T4V; 1TA2; 1TA6; 1TB6; 1TBZ; 1THP; 1THR; 1THS; 1TMB; 1TMT; 1TMU; 1TOM; 1TQ0; 1TQ7; 1TWX; 1UMA; 1UVS; 1VR1; 1VZQ; 1W7G; 1WAY; 1WBG; 1XM1; 1XMN; 1YPE; 1YPG; 1YPJ; 1YPK; 1YPL; 1YPM; 1Z71; 1Z8I; 1Z8J; 1ZGI; 1ZGV; 1ZRB; 2A0Q; 2A2X; 2A45; 2AFQ; 2ANK; 2ANM; 2B5T; 2BDY; 2BVR; 2BVS; 2BVX; 2BXT; 2BXU; 2C8W; 2C8X; 2C8Y; 2C8Z; 2C90; 2C93; 2CF8; 2CF9; 2CN0; 2FEQ; 2FES; 2GDE; 2GP9; 2H9T; 2HGT; 2HNT; 2HPP; 2HPQ; 2HWL; 2JH0; 2JH5; 2JH6; 2OD3; 2PGB; 2PGQ; 2PKS; 2PW8; 2R2M; 2THF; 2UUF; 2UUJ; 2UUK; 2V3H; 2V3O; 2ZC9; 2ZDA; 2ZDV; 2ZF0; 2ZFF; 2ZFP; 2ZFQ; 2ZFR; 2ZG0; 2ZGB; 2ZGX; 2ZHE; 2ZHF; 2ZHQ; 2ZHW; 2ZI2; 2ZIQ; 2ZNK; 2ZO3; 3B23; 3B9F; 3BEF; 3BEI; 3BF6; 3BIU; 3BIV; 3BV9; 3C1K; 3C27; 3D49; 3DA9; 3DD2; 3DHK; 3DT0; 3DUX; 3E6P; 3EE0; 3EGK; 3EQ0; 3F68; 3GIC; 3GIS; 3HAT; 3HKJ; 3HTC; 3JZ1; 3JZ2; 3K65; 3LDX; 3LU9; 3NXP; 3P17; 3P6Z; 3P70; 3PMH; 3PO1; 3QDZ; 3QGN; 3QLP; 3QTO; 3QTV; 3QWC; 3QX5; 3R3G; 3RLW; 3RLY; 3RM0; 3RM2; 3RML; 3RMM; 3RMN; 3RMO; 3S7H; 3S7K; 3SHA; 3SHC; 3SI3; 3SI4; 3SQE; 3SQH; 3SV2; 3T5F; 3TU7; 3U69; 3U8O; 3U8R; 3U8T; 3U98; 3U9A; 3UTU; 3UWJ; 3VXE; 3VXF; 4AX9; 4AYV; 4AYY; 4AZ2; 4BAH; 4BAK; 4BAM; 4BAN; 4BAO; 4BAQ; 4BOH; 4CH2; 4CH8; 4DIH; 4DII; 4DT7; 4DY7; 4E05; 4E06; 4E7R; 4H6S; 4H6T; 4HFP; 4HTC; 4HZH; 4I7Y; 4LOY; 4LXB; 4LZ1; 4LZ4; 4MLF; 4N3L; 4NZE; 4NZQ; 4O03; 4RKJ; 4RKO; 4RN6; 4THN; 4UD9; 4UDW; 4UE7; 4UEH; 4YES; 5AF9; 5AFY; 5AFZ; 5AHG; 5E8E; 5GDS; 7KME; 8KME
2	F7	P08709	Coagulation factor VII	hsa04610	1BF9; 1CVW; 1DAN; 1DVA; 1F7E; 1F7M; 1FAK; 1FF7; 1FFM; 1J9C; 1JBU; 1KLI; 1KLJ; 1NL8; 1O5D; 1QFK; 1W0Y; 1W2K; 1W7X; 1W8B; 1WQV; 1WSS; 1WTG; 1WUN; 1WV7; 1YGC; 1Z6J; 2A2Q; 2AEI; 2AER; 2B7D; 2B8O; 2BZ6; 2C4F; 2EC9; 2F9B; 2FIR; 2FLB; 2FLR; 2PUQ; 2ZP0; 2ZWL; 2ZZU; 3ELA; 3TH2; 3TH3; 3TH4; 4IBL; 4ISH; 4ISI; 4JYU; 4JYV; 4JZD; 4JZE; 4JZF; 4NA9; 4NG9; 4NGA; 4X8S; 4X8T; 4X8U; 4X8V; 4YT6; 4YT7; 4ZXX; 4ZXY
3	F10	P00742	Coagulation factor X	hsa04610	1C5M; 1EZQ; 1F0R; 1F0S; 1FAX; 1FJS; 1FXY; 1G2L; 1G2M; 1HCG; 1IOE; 1IQE; 1IQF; 1IQG; 1IQH; 1IQI; 1IQJ; 1IQK; 1IQL; 1IQM; 1IQN; 1KSN; 1LPG; 1LPK; 1LPZ; 1LQD; 1MQ5; 1MQ6; 1MSX; 1NFU; 1NFW; 1NFX; 1NFY; 1NL8; 1P0S; 1V3X; 1WU1; 1XKA; 1XKB; 1Z6E; 2BMG; 2BOH; 2BOK; 2BQ6; 2BQ7; 2BQW; 2CJI; 2D1J; 2EI6; 2EI7; 2EI8; 2FZZ; 2G00; 2GD4; 2H9E; 2J2U; 2J34; 2J38; 2J4I; 2J94; 2J95; 2JKH; 2P16; 2P3F; 2P3T; 2P3U; 2P93; 2P94; 2P95; 2PHB; 2PR3; 2Q1J; 2RA0; 2UWL; 2UWO; 2UWP; 2VH0; 2VH6; 2VVC; 2VVU; 2VVV; 2VWL; 2VWM; 2VWN; 2VWO; 2W26; 2W3I; 2W3K; 2WYG; 2WYJ; 2XBV; 2XBW; 2XBX; 2XBY; 2XC0; 2XC4; 2XC5; 2Y5F; 2Y5G; 2Y5H; 2Y7X; 2Y7Z; 2Y80; 2Y81; 2Y82; 3CEN; 3CS7; 3ENS; 3FFG; 3HPT; 3IIT; 3K9X; 3KL6; 3KQB; 3KQC; 3KQD; 3KQE; 3LIW; 3M36; 3M37; 3Q3K; 3SW2; 3TK5; 3TK6; 4A7I; 4BTI; 4BTT; 4BTU; 4Y6D; 4Y71; 4Y76; 4Y79; 4Y7A; 4Y7B
4	F8	P00451	Coagulation factor VIII	hsa04610	1CFG; 1D7P; 1FAC; 1IQD; 2R7E; 3CDZ; 3HNB; 3HNY; 3HOB; 3J2Q; 3J2S; 4BDV; 4KI5; 4PT6
5	F11	P03951	Coagulation factor XI	hsa04610	1XX9; 1XXD; 1XXF; 1ZHM; 1ZHP; 1ZHR; 1ZJD; 1ZLR; 1ZMJ; 1ZML; 1ZMN; 1ZOM; 1ZPB; 1ZPC; 1ZPZ; 1ZRK; 1ZSJ; 1ZSK; 1ZSL; 1ZTJ; 1ZTK; 1ZTL; 2F83; 2FDA; 2J8J; 2J8L; 3BG8; 3SOR; 3SOS; 4CR5; 4CR9; 4CRA; 4CRB; 4CRC; 4CRD; 4CRE; 4CRF; 4CRG; 4NA7; 4NA8; 4TY6; 4TY7; 4WXI; 4X6M; 4X6N; 4X6O; 4X6P; 4Y8X; 4Y8Y; 4Y8Z
6	GGCX	P38435	Vitamin K-dependent gamma-carboxylase	hsa00130	NA
7	LRP1	Q07954	Prolow-density lipoprotein receptor-related protein 1	hsa04979; hsa05010; hsa05144	1CR8; 1D2L; 1J8E; 2FYJ; 2FYL; 2KNX; 2KNY

20 predicted interactions (targets) of input drug (DB00100): Coagulation Factor IX (Recombinant)

No.	Gene	UniProt ID	Protein Name	Pathway	PDB	Confidence score
1	FGA	P02671	Fibrinogen alpha chain	hsa04610; hsa04611	1BBR; 1DM4; 1FPH; 1FZA; 1FZB; 1FZC; 1FZD; 1FZE; 1FZF; 1FZG; 1LT9; 1LTJ; 1N86; 1N8E; 1RE3; 1RE4; 1RF0; 1RF1; 1YCP; 2A45; 2FFD; 2H43; 2HLO; 2HOD; 2HPC; 2OYH; 2OYI; 2Q9I; 2XNX; 2XNY; 2Z4E; 3AT0; 3BVH; 3E1I; 3GHG; 3H32; 3HUS; 4F27; 5CFA	41.6%
2	F5	P12259	Coagulation factor V	hsa04610	1CZS; 1CZT; 1CZV; 1FV4; 1Y61; 3P6Z; 3P70; 3S9C	40.7%
3	PROS1	P07225	Vitamin K-dependent protein S	hsa04610	1Z6C	39.2%
4	F9	P00740	Coagulation factor IX	hsa04610	1CFH; 1CFI; 1EDM; 1IXA; 1MGX; 1NL0; 1RFN; 2WPH; 2WPI; 2WPJ; 2WPK; 2WPL; 2WPM; 3KCG; 3LC3; 3LC5; 4WM0; 4WMA; 4WMB; 4WMI; 4WMK; 4WN2; 4WNH; 4YZU; 4Z0K; 4ZAE; 5EGM	38.1%
5	CANX	P27824	Calnexin	hsa04141; hsa04145; hsa04612; hsa04918; hsa05166	NA	30.7%
6	NQO2	P16083	Ribosyldihydronicotinamide dehydrogenase [quinone]	NA	1QR2; 1SG0; 1XI2; 1ZX1; 2BZS; 2QMY; 2QMZ; 2QR2; 2QWX; 2QX4; 2QX6; 2QX8; 2QX9; 3FW1; 3G5M; 3GAM; 3NFR; 3NHF; 3NHJ; 3NHK; 3NHL; 3NHP; 3NHR; 3NHS; 3NHU; 3NHW; 3NHY; 3O2N; 3O73; 3OVM; 3OWH; 3OWX; 3OX1; 3OX2; 3OX3; 3TE7; 3TEM; 3TZB; 3UXE; 3UXH; 4FGJ; 4FGK; 4FGL; 4GQI; 4GR9; 4QOD; 4QOE; 4QOF; 4QOG; 4QOH; 4QOI; 4QOJ; 4U7F; 4U7G; 4U7H	28.5%
7	BGLAP	P02818	Osteocalcin	hsa04928	NA	27.9%
8	FGB	P02675	Fibrinogen beta chain	hsa04610; hsa04611	1FZA; 1FZB; 1FZC; 1FZE; 1FZF; 1FZG; 1LT9; 1LTJ; 1N86; 1N8E; 1RE3; 1RE4; 1RF0; 1RF1; 2A45; 2FFD; 2H43; 2HLO; 2HOD; 2HPC; 2OYH; 2OYI; 2Q9I; 2XNX; 2XNY; 2Z4E; 3BVH; 3E1I; 3GHG; 3H32; 3HUS	27.7%
9	FGG	P02679	Fibrinogen gamma chain	hsa04610; hsa04611; hsa05150	1DUG; 1FIB; 1FIC; 1FID; 1FZA; 1FZB; 1FZC; 1FZE; 1FZF; 1FZG; 1LT9; 1LTJ; 1N86; 1N8E; 1RE3; 1RE4; 1RF0; 1RF1; 2A45; 2FFD; 2FIB; 2H43; 2HLO; 2HOD; 2HPC; 2HWL; 2OYH; 2OYI; 2Q9I; 2VDO; 2VDP; 2VDQ; 2VDR; 2VR3; 2XNX; 2XNY; 2Y7L; 2Z4E; 3BVH; 3E1I; 3FIB; 3GHG; 3H32; 3HUS; 4B60	27.5%
10	CALR	P27797	Calreticulin	hsa04141; hsa04145; hsa04612; hsa05142; hsa05163; hsa05166; hsa05170	2CLR; 3DOW; 3POS; 3POW	25.1%
11	PROC	P04070	Vitamin K-dependent protein C	hsa04610	1AUT; 1LQV; 1PCU; 2PCT; 3F6U; 3JTC; 4DT7	24.5%
12	PROZ	P22891	Vitamin K-dependent protein Z	NA	3F1S; 3H5C	24.1%
13	NQO1	P15559	NAD(P)H dehydrogenase [quinone] 1	hsa00130; hsa05200; hsa05225; hsa05418	1D4A; 1DXO; 1GG5; 1H66; 1H69; 1KBO; 1KBQ; 1QBG; 2F1O; 3JSX; 4CET; 4CF6	23.0%
14	F13B	P05160	Coagulation factor XIII B chain	hsa04610	NA	21.4%
15	ANXA2	P07355	Annexin A2	NA	1W7B; 1XJL; 2HYU; 2HYV; 2HYW; 4DRW; 4FTG; 4HRH	21.3%
16	GSTM4	Q03013	Glutathione S-transferase Mu 4	hsa00480; hsa00980; hsa00982; hsa00983; hsa01524; hsa05200; hsa05204; hsa05225; hsa05418	4GTU	20.8%
17	KLKB1	P03952	Plasma kallikrein	hsa04610	2ANW; 2ANY; 4OGX; 4OGY; 4ZJ4; 4ZJ5; 4ZJ6	20.7%
18	THBD	P07204	Thrombomodulin	hsa04610; hsa04933; hsa05418	1ADX; 1DQB; 1DX5; 1EGT; 1FGD; 1FGE; 1HLT; 1TMR; 1ZAQ; 2ADX; 3GIS	20.4%
19	LMAN1	P49257	Protein ERGIC-53	hsa04141	3A4U; 3LCP; 3WHT; 3WHU; 3WNX; 4GKX; 4GKY	20.3%
20	KRT8	P05787	Keratin, type II cytoskeletal 8	NA	NA	20.2%