QuartataWeb 1.0

9 known interactions (targets) of input drug (DB02746): Phthalic Acid

No.	Gene	UniProt ID	Protein Name	Pathway	PDB
1	ESR1	P03372	Estrogen receptor	hsa01522; hsa04915; hsa04917; hsa04919; hsa04961; hsa05200; hsa05205; hsa05224	1A52; 1AKF; 1ERE; 1ERR; 1G50; 1GWQ; 1GWR; 1HCP; 1HCQ; 1L2I; 1PCG; 1QKT; 1QKU; 1R5K; 1SJ0; 1UOM; 1X7E; 1X7R; 1XP1; 1XP6; 1XP9; 1XPC; 1XQC; 1YIM; 1YIN; 1ZKY; 2AYR; 2B1V; 2B1Z; 2B23; 2BJ4; 2FAI; 2G44; 2G5O; 2I0J; 2IOG; 2IOK; 2JF9; 2JFA; 2LLO; 2LLQ; 2OCF; 2OUZ; 2P15; 2POG; 2Q6J; 2Q70; 2QA6; 2QA8; 2QAB; 2QE4; 2QGT; 2QGW; 2QH6; 2QR9; 2QSE; 2QXM; 2QXS; 2QZO; 2R6W; 2R6Y; 2YAT; 2YJA; 3CBM; 3CBO; 3CBP; 3DT3; 3ERD; 3ERT; 3HLV; 3HM1; 3L03; 3OS8; 3OS9; 3OSA; 3Q95; 3Q97; 3UU7; 3UUA; 3UUC; 3UUD; 4AA6; 4DMA; 4IU7; 4IUI; 4IV2; 4IV4; 4IVW; 4IVY; 4IW6; 4IW8; 4IWC; 4IWF; 4JC3; 4JDD; 4MG5; 4MG6; 4MG7; 4MG8; 4MG9; 4MGA; 4MGB; 4MGC; 4MGD; 4O6F; 4PP6; 4PPP; 4PPS; 4PXM; 4Q13; 4Q50; 4TUZ; 4TV1; 4ZN9; 5AAU; 5AAV; 5AK2
2	PGR	P06401	Progesterone receptor	hsa04114; hsa04914; hsa04915; hsa05224	1A28; 1E3K; 1SQN; 1SR7; 1ZUC; 2C7A; 2OVH; 2OVM; 2W8Y; 3D90; 3G8O; 3HQ5; 3KBA; 3ZR7; 3ZRA; 3ZRB; 4A2J; 4APU; 4OAR
3	RXRB	P28702	Retinoic acid receptor RXR-beta	hsa03320; hsa04659; hsa04919; hsa04920; hsa04928; hsa05200; hsa05202; hsa05216; hsa05222; hsa05223; hsa05226	1H9U; 1UHL
4	ESR2	Q92731	Estrogen receptor beta	hsa01522; hsa04915; hsa04917; hsa05200; hsa05224	1L2J; 1NDE; 1QKM; 1U3Q; 1U3R; 1U3S; 1U9E; 1X76; 1X78; 1X7B; 1X7J; 1YY4; 1YYE; 1ZAF; 2FSZ; 2GIU; 2I0G; 2JJ3; 2NV7; 2QTU; 2YJD; 2YLY; 2Z4B; 3OLL; 3OLS; 3OMO; 3OMP; 3OMQ; 4J24; 4J26
5	RXRA	P19793	Retinoic acid receptor RXR-alpha	hsa03320; hsa04151; hsa04659; hsa04919; hsa04920; hsa04928; hsa04932; hsa04976; hsa05160; hsa05200; hsa05202; hsa05216; hsa05222; hsa05223; hsa05226	1BY4; 1DSZ; 1FBY; 1FM6; 1FM9; 1G1U; 1G5Y; 1K74; 1LBD; 1MV9; 1MVC; 1MZN; 1R0N; 1RDT; 1RXR; 1XLS; 1XV9; 1XVP; 1YNW; 2ACL; 2NLL; 2P1T; 2P1U; 2P1V; 2ZXZ; 2ZY0; 3DZU; 3DZY; 3E00; 3E94; 3FAL; 3FC6; 3FUG; 3H0A; 3KWY; 3NSP; 3NSQ; 3OAP; 3OZJ; 3PCU; 3R29; 3R2A; 3R5M; 3UVV; 4CN2; 4CN3; 4CN5; 4CN7; 4J5W; 4J5X; 4K4J; 4K6I; 4M8E; 4M8H; 4N5G; 4N8R; 4NQA; 4OC7; 4POH; 4POJ; 4PP3; 4PP5; 4RFW; 4RMC; 4RMD; 4RME; 4ZO1
6	PPARD	Q03181	Peroxisome proliferator-activated receptor delta	hsa03320; hsa04310; hsa05200; hsa05221	1GWX; 1Y0S; 2AWH; 2B50; 2BAW; 2ENV; 2GWX; 2J14; 2Q5G; 2XYJ; 2XYW; 2XYX; 2ZNP; 2ZNQ; 3D5F; 3DY6; 3ET2; 3GWX; 3GZ9; 3OZ0; 3PEQ; 3SP9; 3TKM
7	RXRG	P48443	Retinoic acid receptor RXR-gamma	hsa03320; hsa04659; hsa04919; hsa04920; hsa04928; hsa05200; hsa05202; hsa05216; hsa05222; hsa05223; hsa05226	2GL8
8	PPARG	P37231	Peroxisome proliferator-activated receptor gamma	hsa03320; hsa04152; hsa04211; hsa04380; hsa04714; hsa05016; hsa05200; hsa05202; hsa05216	1FM6; 1FM9; 1I7I; 1K74; 1KNU; 1NYX; 1PRG; 1RDT; 1WM0; 1ZEO; 1ZGY; 2ATH; 2F4B; 2FVJ; 2G0G; 2G0H; 2GTK; 2HFP; 2HWQ; 2HWR; 2I4J; 2I4P; 2I4Z; 2OM9; 2P4Y; 2POB; 2PRG; 2Q59; 2Q5P; 2Q5S; 2Q61; 2Q6R; 2Q6S; 2Q8S; 2QMV; 2VSR; 2VST; 2VV0; 2VV1; 2VV2; 2VV3; 2VV4; 2XKW; 2YFE; 2ZK0; 2ZK1; 2ZK2; 2ZK3; 2ZK4; 2ZK5; 2ZK6; 2ZNO; 2ZVT; 3ADS; 3ADT; 3ADU; 3ADV; 3ADW; 3ADX; 3AN3; 3AN4; 3B0Q; 3B0R; 3B1M; 3B3K; 3BC5; 3CDP; 3CDS; 3CS8; 3CWD; 3D6D; 3DZU; 3DZY; 3E00; 3ET0; 3ET3; 3FEJ; 3FUR; 3G9E; 3GBK; 3H0A; 3HO0; 3HOD; 3IA6; 3K8S; 3KMG; 3LMP; 3NOA; 3OSI; 3OSW; 3PBA; 3PO9; 3PRG; 3QT0; 3R5N; 3R8A; 3R8I; 3S9S; 3SZ1; 3T03; 3TY0; 3U9Q; 3V9T; 3V9V; 3V9Y; 3VJH; 3VJI; 3VN2; 3VSO; 3VSP; 3WJ4; 3WJ5; 3WMH; 3X1H; 3X1I; 4A4V; 4A4W; 4CI5; 4E4K; 4E4Q; 4EM9; 4EMA; 4F9M; 4FGY; 4HEE; 4JAZ; 4JL4; 4L96; 4L98; 4O8F; 4OJ4; 4PRG; 4PVU; 4PWL; 4R2U; 4R6S; 4XLD; 4XTA; 4XUM; 4Y29
9	PPARA	Q07869	Peroxisome proliferator-activated receptor alpha	hsa03320; hsa04024; hsa04920; hsa04922; hsa04931; hsa04932; hsa05160	1I7G; 1K7L; 1KKQ; 2NPA; 2P54; 2REW; 2ZNN; 3ET1; 3FEI; 3G8I; 3KDT; 3KDU; 3SP6; 3VI8; 4BCR; 4CI4

20 predicted interactions (targets) of input drug (DB02746): Phthalic Acid

No.	Gene	UniProt ID	Protein Name	Pathway	PDB	Confidence score
1	NCOA2	Q15596	Nuclear receptor coactivator 2	hsa04915; hsa04919	1GWQ; 1GWR; 1M2Z; 1MV9; 1MVC; 1MZN; 1P93; 1T63; 1T65; 1UHL; 1YOK; 1ZDT; 1ZDU; 1ZKY; 2AO6; 2B1V; 2B1Z; 2B23; 2FAI; 2G44; 2G5O; 2LDC; 2P15; 2P1T; 2P1U; 2P1V; 2Q7J; 2Q7L; 2YJD; 2ZXZ; 2ZY0; 3A9E; 3CLD; 3DZU; 3DZY; 3E00; 3E7C; 3E94; 3ERD; 3FUG; 3GN8; 3K22; 3K23; 3KWY; 3KYT; 3L0E; 3L0J; 3L0L; 3O1D; 3O1E; 3OAP; 3OZJ; 3PCU; 3PLZ; 3Q95; 3Q97; 3R5M; 3UP0; 3UP3; 4CSJ; 4DOS; 4E2J; 4FHH; 4FHI; 4IA1; 4IA2; 4IA3; 4IA7; 4IQR; 4IU7; 4IUI; 4IV2; 4IV4; 4IVW; 4IVY; 4IW6; 4IW8; 4IWC; 4IWF; 4K4J; 4K6I; 4M8E; 4M8H; 4NIE; 4NQA; 4OC7; 4P6W; 4P6X; 4POH; 4POJ; 4PP3; 4PP5; 4PP6; 4PPP; 4PPS; 4PXM; 4Q0A; 4QE6; 4QE8; 4RFW; 4RMC; 4RMD; 4RME; 4RUO; 4WG0; 4ZN9; 4ZO1	50.0%
2	SHBG	P04278	Sex hormone-binding globulin	NA	1D2S; 1F5F; 1KDK; 1KDM; 1LHN; 1LHO; 1LHU; 1LHV; 1LHW	49.1%
3	NCOA1	Q15788	Nuclear receptor coactivator 1	hsa04915; hsa04919; hsa05200; hsa05224	1FM6; 1FM9; 1K4W; 1K74; 1K7L; 1KV6; 1N4H; 1NQ7; 1NRL; 1P8D; 1PZL; 1RDT; 1TFC; 1U3R; 1U3S; 1X76; 1X78; 1X7B; 1X7J; 1XIU; 1XV9; 1XVP; 1YY4; 1YYE; 1ZAF; 2A3I; 2C52; 2FVJ; 2GTK; 2HBH; 2HC4; 2HCD; 2HFP; 2NPA; 2NV7; 2P54; 2PRG; 3BEJ; 3BQD; 3CTB; 3CWD; 3DCT; 3DCU; 3DR1; 3ET1; 3ET3; 3FEI; 3FEJ; 3FUR; 3FXV; 3G8I; 3G9E; 3GYT; 3GYU; 3H0A; 3HC5; 3HC6; 3HVL; 3IPQ; 3IPS; 3IPU; 3KMR; 3LMP; 3OKH; 3OKI; 3OLF; 3OLL; 3OLS; 3OMK; 3OMM; 3OMO; 3OMP; 3OMQ; 3OOF; 3OOK; 3P88; 3P89; 3QT0; 3RUT; 3RUU; 3RVF; 3S9S; 3T03; 3UU7; 3UUA; 3UUD; 3V9Y; 3VN2; 4DK7; 4DK8; 4DM6; 4DM8; 4DQM; 4F9M; 4FGY; 4G1D; 4G1Y; 4G1Z; 4G20; 4G21; 4G2H; 4HEE; 4J5X; 4JYG; 4JYH; 4JYI; 4MG5; 4MG6; 4MG7; 4MG8; 4MG9; 4MGA; 4MGB; 4MGC; 4MGD; 4RUJ; 4RUP; 4TUZ; 4TV1; 4Y29; 5A86; 5AVI; 5AVL	44.7%
4	ACSL4	O60488	Long-chain-fatty-acid--CoA ligase 4	hsa00061; hsa00071; hsa01100; hsa01212; hsa03320; hsa04146; hsa04216; hsa04714; hsa04920	NA	44.3%
5	AR	P10275	Androgen receptor	hsa04114; hsa05200; hsa05215	1E3G; 1GS4; 1T5Z; 1T63; 1T65; 1XJ7; 1XOW; 1XQ3; 1Z95; 2AM9; 2AMA; 2AMB; 2AO6; 2AX6; 2AX7; 2AX8; 2AX9; 2AXA; 2HVC; 2OZ7; 2PIO; 2PIP; 2PIQ; 2PIR; 2PIT; 2PIU; 2PIV; 2PIW; 2PIX; 2PKL; 2PNU; 2Q7I; 2Q7J; 2Q7K; 2Q7L; 2YHD; 2YLO; 2YLP; 2YLQ; 2Z4J; 3B5R; 3B65; 3B66; 3B67; 3B68; 3BTR; 3L3X; 3L3Z; 3RLJ; 3RLL; 3V49; 3V4A; 3ZQT; 4HLW; 4K7A; 4OEA; 4OED; 4OEY; 4OEZ; 4OFR; 4OFU; 4OGH; 4OH5; 4OH6; 4OHA; 4OIL; 4OIU; 4OJ9; 4OJB; 4OK1; 4OKB; 4OKT; 4OKW; 4OKX; 4OLM; 4QL8; 4U4K	44.2%
6	NR1I2	O75469	Nuclear receptor subfamily 1 group I member 2	NA	1ILG; 1ILH; 1M13; 1NRL; 1SKX; 2O9I; 2QNV; 3CTB; 3HVL; 3R8D; 4J5W; 4J5X; 4NY9; 4S0S; 4S0T; 4X1F; 4X1G; 4XAO; 4XHD; 5A86	36.6%
7	DPP4	P27487	Dipeptidyl peptidase 4	hsa04974	1J2E; 1N1M; 1NU6; 1NU8; 1PFQ; 1R9M; 1R9N; 1RWQ; 1TK3; 1TKR; 1U8E; 1W1I; 1WCY; 1X70; 2AJL; 2BGN; 2BGR; 2BUB; 2FJP; 2G5P; 2G5T; 2G63; 2HHA; 2I03; 2I78; 2IIT; 2IIV; 2JID; 2OAG; 2OGZ; 2OLE; 2ONC; 2OPH; 2OQI; 2OQV; 2P8S; 2QJR; 2QKY; 2QOE; 2QT9; 2QTB; 2RGU; 2RIP; 3BJM; 3C43; 3C45; 3CCB; 3CCC; 3D4L; 3EIO; 3F8S; 3G0B; 3G0C; 3G0D; 3G0G; 3H0C; 3HAB; 3HAC; 3KWF; 3KWJ; 3NOX; 3O95; 3O9V; 3OC0; 3OPM; 3Q0T; 3Q8W; 3QBJ; 3SWW; 3SX4; 3VJK; 3VJL; 3VJM; 3W2T; 3WQH; 4A5S; 4DSA; 4DSZ; 4DTC; 4G1F; 4J3J; 4JH0; 4KR0; 4L72; 4LKO; 4N8D; 4N8E; 4PNZ; 4PV7; 4QZV	28.2%
8	NR3C2	P08235	Mineralocorticoid receptor	hsa04960	1Y9R; 1YA3; 2A3I; 2AA2; 2AA5; 2AA6; 2AA7; 2AAX; 2AB2; 2ABI; 2OAX; 3VHU; 3VHV; 3WFF; 3WFG; 4PF3; 4TNT	28.2%
9	GLTP	Q9NZD2	Glycolipid transfer protein	NA	1SWX; 1SX6; 2EUK; 2EUM; 2EVD; 2EVL; 2EVS; 2EVT; 3RIC; 3RWV; 3RZN; 3S0I; 3S0K; 4GH0; 4GHP; 4GHS; 4GIX; 4GJQ; 4GVT; 4GXD; 4GXG; 4H2Z	28.0%
10	SLC8A1	P32418	Sodium/calcium exchanger 1	hsa04020; hsa04022; hsa04260; hsa04261; hsa04371; hsa04740; hsa04961; hsa04974; hsa04978; hsa05410; hsa05412; hsa05414	NA	26.5%
11	ESRRG	P62508	Estrogen-related receptor gamma	NA	1KV6; 1TFC; 1VJB; 2E2R; 2EWP; 2GP7; 2GPO; 2GPP; 2GPU; 2GPV; 2P7A; 2P7G; 2P7Z; 2ZAS; 2ZBS; 2ZKC	25.7%
12	RARA	P10276	Retinoic acid receptor alpha	hsa04659; hsa04915; hsa05200; hsa05202; hsa05221	1DKF; 1DSZ; 3A9E; 3KMR; 3KMZ; 4DQM	25.2%
13	HSD17B1	P14061	Estradiol 17-beta-dehydrogenase 1	hsa00140; hsa01100; hsa04913	1A27; 1BHS; 1DHT; 1EQU; 1FDS; 1FDT; 1FDU; 1FDV; 1FDW; 1I5R; 1IOL; 1JTV; 1QYV; 1QYW; 1QYX; 3DEY; 3DHE; 3HB4; 3HB5; 3KLM; 3KLP; 3KM0	24.0%
14	SREBF1	P36956	Sterol regulatory element-binding protein 1	hsa04152; hsa04910; hsa04931; hsa04932	1AM9	23.8%
15	NR1I3	Q14994	Nuclear receptor subfamily 1 group I member 3	NA	1XV9; 1XVP	23.3%
16	mmp20	O43923	Matrix metalloproteinase-25	NA	NA	23.0%
17	PTGS1	P23219	Prostaglandin G/H synthase 1	hsa00590; hsa01100; hsa04611; hsa04726; hsa04923	NA	22.9%
18	F2	P00734	Prothrombin	hsa04080; hsa04610; hsa04810	1A2C; 1A3B; 1A3E; 1A46; 1A4W; 1A5G; 1A61; 1ABI; 1ABJ; 1AD8; 1AE8; 1AFE; 1AHT; 1AI8; 1AIX; 1AWF; 1AWH; 1AY6; 1B5G; 1B7X; 1BA8; 1BB0; 1BCU; 1BHX; 1BMM; 1BMN; 1BTH; 1C1U; 1C1V; 1C1W; 1C4U; 1C4V; 1C4Y; 1C5L; 1C5N; 1C5O; 1CA8; 1D3D; 1D3P; 1D3Q; 1D3T; 1D4P; 1D6W; 1D9I; 1DE7; 1DIT; 1DM4; 1DOJ; 1DWB; 1DWC; 1DWD; 1DWE; 1DX5; 1E0F; 1EB1; 1EOJ; 1EOL; 1FPC; 1FPH; 1G30; 1G32; 1G37; 1GHV; 1GHW; 1GHX; 1GHY; 1GJ4; 1GJ5; 1H8D; 1H8I; 1HAG; 1HAH; 1HAI; 1HAO; 1HAP; 1HBT; 1HDT; 1HGT; 1HLT; 1HUT; 1HXE; 1HXF; 1IHS; 1IHT; 1JMO; 1JOU; 1JWT; 1K21; 1K22; 1KTS; 1KTT; 1LHC; 1LHD; 1LHE; 1LHF; 1LHG; 1MH0; 1MU6; 1MU8; 1MUE; 1NM6; 1NO9; 1NRN; 1NRO; 1NRP; 1NRQ; 1NRR; 1NRS; 1NT1; 1NU7; 1NU9; 1NY2; 1NZQ; 1O0D; 1O2G; 1O5G; 1OOK; 1OYT; 1P8V; 1PPB; 1QBV; 1QHR; 1QJ1; 1QJ6; 1QJ7; 1QUR; 1RD3; 1RIW; 1SB1; 1SFQ; 1SG8; 1SGI; 1SHH; 1SL3; 1SR5; 1T4U; 1T4V; 1TA2; 1TA6; 1TB6; 1TBZ; 1THP; 1THR; 1THS; 1TMB; 1TMT; 1TMU; 1TOM; 1TQ0; 1TQ7; 1TWX; 1UMA; 1UVS; 1VR1; 1VZQ; 1W7G; 1WAY; 1WBG; 1XM1; 1XMN; 1YPE; 1YPG; 1YPJ; 1YPK; 1YPL; 1YPM; 1Z71; 1Z8I; 1Z8J; 1ZGI; 1ZGV; 1ZRB; 2A0Q; 2A2X; 2A45; 2AFQ; 2ANK; 2ANM; 2B5T; 2BDY; 2BVR; 2BVS; 2BVX; 2BXT; 2BXU; 2C8W; 2C8X; 2C8Y; 2C8Z; 2C90; 2C93; 2CF8; 2CF9; 2CN0; 2FEQ; 2FES; 2GDE; 2GP9; 2H9T; 2HGT; 2HNT; 2HPP; 2HPQ; 2HWL; 2JH0; 2JH5; 2JH6; 2OD3; 2PGB; 2PGQ; 2PKS; 2PW8; 2R2M; 2THF; 2UUF; 2UUJ; 2UUK; 2V3H; 2V3O; 2ZC9; 2ZDA; 2ZDV; 2ZF0; 2ZFF; 2ZFP; 2ZFQ; 2ZFR; 2ZG0; 2ZGB; 2ZGX; 2ZHE; 2ZHF; 2ZHQ; 2ZHW; 2ZI2; 2ZIQ; 2ZNK; 2ZO3; 3B23; 3B9F; 3BEF; 3BEI; 3BF6; 3BIU; 3BIV; 3BV9; 3C1K; 3C27; 3D49; 3DA9; 3DD2; 3DHK; 3DT0; 3DUX; 3E6P; 3EE0; 3EGK; 3EQ0; 3F68; 3GIC; 3GIS; 3HAT; 3HKJ; 3HTC; 3JZ1; 3JZ2; 3K65; 3LDX; 3LU9; 3NXP; 3P17; 3P6Z; 3P70; 3PMH; 3PO1; 3QDZ; 3QGN; 3QLP; 3QTO; 3QTV; 3QWC; 3QX5; 3R3G; 3RLW; 3RLY; 3RM0; 3RM2; 3RML; 3RMM; 3RMN; 3RMO; 3S7H; 3S7K; 3SHA; 3SHC; 3SI3; 3SI4; 3SQE; 3SQH; 3SV2; 3T5F; 3TU7; 3U69; 3U8O; 3U8R; 3U8T; 3U98; 3U9A; 3UTU; 3UWJ; 3VXE; 3VXF; 4AX9; 4AYV; 4AYY; 4AZ2; 4BAH; 4BAK; 4BAM; 4BAN; 4BAO; 4BAQ; 4BOH; 4CH2; 4CH8; 4DIH; 4DII; 4DT7; 4DY7; 4E05; 4E06; 4E7R; 4H6S; 4H6T; 4HFP; 4HTC; 4HZH; 4I7Y; 4LOY; 4LXB; 4LZ1; 4LZ4; 4MLF; 4N3L; 4NZE; 4NZQ; 4O03; 4RKJ; 4RKO; 4RN6; 4THN; 4UD9; 4UDW; 4UE7; 4UEH; 4YES; 5AF9; 5AFY; 5AFZ; 5AHG; 5E8E; 5GDS; 7KME; 8KME	22.3%
19	RARB	P10826	Retinoic acid receptor beta	hsa05200; hsa05222; hsa05223; hsa05226	1HRA; 1XAP; 4DM6; 4DM8; 4JYG; 4JYH; 4JYI	22.3%
20	SRD5A1	P18405	3-oxo-5-alpha-steroid 4-dehydrogenase 1	hsa00140	NA	21.7%