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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: P09211
No. Gene UniProt ID Protein Name Pathway PDB
1 GSTP1 P09211 Glutathione S-transferase P hsa00480; hsa00980; hsa00982; hsa00983; hsa01524; hsa05200; hsa05204; hsa05215; hsa05225; hsa05418


25 known interactions (drugs) of input target (GSTP1): Glutathione S-transferase P
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image
1 Experimental SmallMoleculeDrug DB01834 (9R,10R)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene Thumb
2 Experimental SmallMoleculeDrug DB07849 S-NONYL-CYSTEINE Thumb
3 Approved;
Investigational		 SmallMoleculeDrug DB04339 Carbocisteine Thumb
4 Approved SmallMoleculeDrug DB00363 Clozapine Thumb
5 Experimental SmallMoleculeDrug DB03686 S-(P-Nitrobenzyl)Glutathione Thumb
6 Experimental SmallMoleculeDrug DB03003 Glutathione Sulfonic Acid Thumb
7 Approved;
Investigational;
Vet approved		 SmallMoleculeDrug DB01242 Clomipramine Thumb
8 Investigational SmallMoleculeDrug DB06246 Exisulind Thumb
9 Approved SmallMoleculeDrug DB03619 Deoxycholic Acid Thumb
10 Experimental SmallMoleculeDrug DB03814 2-(N-Morpholino)-Ethanesulfonic Acid Thumb
11 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB00143 Glutathione Thumb
12 Investigational SmallMoleculeDrug DB11831 Dinitrochlorobenzene Thumb
13 Experimental SmallMoleculeDrug DB08370 S-(4-BROMOBENZYL)CYSTEINE Thumb
14 Approved;
Investigational		 SmallMoleculeDrug DB00903 Etacrynic acid Thumb
15 Investigational SmallMoleculeDrug DB13014 Hypericin Thumb
16 Experimental SmallMoleculeDrug DB02633 Cibacron Blue Thumb
17 Investigational SmallMoleculeDrug DB05460 Ezatiostat Thumb
18 Investigational SmallMoleculeDrug DB04972 Canfosfamide Thumb
19 Approved SmallMoleculeDrug DB01015 Sulfamethoxazole Thumb
20 Experimental SmallMoleculeDrug DB04132 S-Hexylglutathione Thumb
21 Approved SmallMoleculeDrug DB00316 Acetaminophen Thumb
22 Investigational;
Withdrawn		 SmallMoleculeDrug DB00197 Troglitazone Thumb
23 Approved;
Investigational		 SmallMoleculeDrug DB09462 Glycerin Thumb
24 Experimental SmallMoleculeDrug DB01915 S-Hydroxycysteine Thumb
25 Approved;
Investigational		 SmallMoleculeDrug DB11672 Curcumin Thumb


20 predicted interactions (drugs) of input target (GSTP1): Glutathione S-transferase P
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image Confidence score
1 Approved;
Investigational		 SmallMoleculeDrug DB00328 Indomethacin Thumb 38.0%
2 Approved;
Investigational;
Withdrawn		 SmallMoleculeDrug DB01041 Thalidomide Thumb 35.9%
3 Experimental;
Illicit;
Investigational		 SmallMoleculeDrug DB01454 Midomafetamine Thumb 33.0%
4 Experimental SmallMoleculeDrug DB03602 S-Benzyl-Glutathione Thumb 33.0%
5 Approved;
Investigational		 SmallMoleculeDrug DB00605 Sulindac Thumb 32.6%
6 Approved;
Investigational;
Vet approved		 SmallMoleculeDrug DB00477 Chlorpromazine Thumb 32.1%
7 Approved;
Investigational		 SmallMoleculeDrug DB01624 Zuclopenthixol Thumb 31.1%
8 Approved;
Experimental		 SmallMoleculeDrug DB03796 Palmitic Acid Thumb 30.8%
9 Approved SmallMoleculeDrug DB00458 Imipramine Thumb 30.4%
10 Investigational SmallMoleculeDrug DB05483 PCL-016 Thumb 30.4%
11 Approved SmallMoleculeDrug DB11273 Dihydroergocornine Thumb 30.3%
12 Withdrawn SmallMoleculeDrug DB04821 Nomifensine Thumb 30.1%
13 Approved SmallMoleculeDrug DB00370 Mirtazapine Thumb 30.1%
14 Approved SmallMoleculeDrug DB00244 Mesalazine Thumb 29.9%
15 Approved;
Nutraceutical		 SmallMoleculeDrug DB00126 Vitamin C Thumb 29.9%
16 Investigational SmallMoleculeDrug DB12695 Phenethyl Isothiocyanate Thumb 29.6%
17 Approved;
Investigational		 SmallMoleculeDrug DB00203 Sildenafil Thumb 28.9%
18 Approved;
Investigational		 SmallMoleculeDrug DB13025 Tiapride Thumb 28.4%
19 Approved;
Nutraceutical		 SmallMoleculeDrug DB13961 Fish oil Thumb 28.3%
20 Approved;
Investigational		 SmallMoleculeDrug DB00714 Apomorphine Thumb 27.8%


  logl

Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.

Contact:

The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.