QuartataWeb
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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: Q9Y2T6
No. Gene UniProt ID Protein Name Pathway PDB
1 GPR55 Q9Y2T6 G-protein coupled receptor 55 NA NA


5 known interactions (drugs) of input target (GPR55): G-protein coupled receptor 55
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image
1 Approved;
Investigational		 SmallMoleculeDrug DB06155 Rimonabant Thumb
2 Approved;
Investigational		 SmallMoleculeDrug DB14011 Nabiximols Thumb
3 Investigational SmallMoleculeDrug DB11755 Tetrahydrocannabivarin Thumb
4 Approved;
Investigational		 SmallMoleculeDrug DB09061 Cannabidiol Thumb
5 Experimental;
Investigational		 BiotechDrug DB14009 Medical Cannabis Thumb


20 predicted interactions (drugs) of input target (GPR55): G-protein coupled receptor 55
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image Confidence score
1 Experimental SmallMoleculeDrug DB02955 Ricinoleic Acid Thumb 39.0%
2 Investigational SmallMoleculeDrug DB14050 Cannabidivarin Thumb 35.7%
3 Approved;
Investigational		 SmallMoleculeDrug DB00486 Nabilone Thumb 35.5%
4 Approved;
Illicit		 SmallMoleculeDrug DB00470 Dronabinol Thumb 35.0%
5 Approved SmallMoleculeDrug DB01744 Camphor Thumb 34.3%
6 Experimental SmallMoleculeDrug DB11345 (S)-camphor Thumb 32.9%
7 Approved SmallMoleculeDrug DB00825 Menthol Thumb 32.8%
8 Approved SmallMoleculeDrug DB04841 Flunarizine Thumb 30.8%
9 Approved;
Investigational		 SmallMoleculeDrug DB09288 Propacetamol Thumb 28.5%
10 Investigational SmallMoleculeDrug DB05077 SLV319 Thumb 26.6%
11 Investigational SmallMoleculeDrug DB05750 AVE-1625 Thumb 25.9%
12 Investigational SmallMoleculeDrug DB05372 CP-945598 Thumb 25.7%
13 Approved SmallMoleculeDrug DB00321 Amitriptyline Thumb 25.4%
14 Investigational SmallMoleculeDrug DB05201 V24343 Thumb 25.3%
15 Approved;
Withdrawn		 SmallMoleculeDrug DB11148 Butamben Thumb 24.5%
16 Approved;
Investigational		 SmallMoleculeDrug DB00568 Cinnarizine Thumb 23.9%
17 Approved;
Investigational		 SmallMoleculeDrug DB06202 Lasofoxifene Thumb 22.6%
18 Approved SmallMoleculeDrug DB06152 Nylidrin Thumb 22.1%
19 Investigational SmallMoleculeDrug DB05885 Seletracetam Thumb 20.0%
20 Approved;
Experimental		 SmallMoleculeDrug DB13746 Bioallethrin Thumb 19.9%


  logl

Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.

Contact:

The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.