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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: P61626
No. Gene UniProt ID Protein Name Pathway PDB
1 LYZ P61626 Lysozyme C hsa04970
133L; 134L; 1B5U; 1B5V; 1B5W; 1B5X; 1B5Y; 1B5Z; 1B7L; 1B7M; 1B7N; 1B7O; 1B7P; 1B7Q; 1B7R; 1B7S; 1BB3; 1BB4; 1BB5; 1C43; 1C45; 1C46; 1C7P; 1CJ6; 1CJ7; 1CJ8; 1CJ9; 1CKC; 1CKD; 1CKF; 1CKG; 1CKH; 1D6P; 1D6Q; 1DI3; 1DI4; 1DI5; 1EQ4; 1EQ5; 1EQE; 1GAY; 1GAZ; 1GB0; 1GB2; 1GB3; 1GB5; 1GB6; 1GB7; 1GB8; 1GB9; 1GBO; 1GBW; 1GBX; 1GBY; 1GBZ; 1GDW; 1GDX; 1GE0; 1GE1; 1GE2; 1GE3; 1GE4; 1GEV; 1GEZ; 1GF0; 1GF3; 1GF4; 1GF5; 1GF6; 1GF7; 1GF8; 1GF9; 1GFA; 1GFE; 1GFG; 1GFH; 1GFJ; 1GFK; 1GFR; 1GFT; 1GFU; 1GFV; 1HNL; 1I1Z; 1I20; 1I22; 1INU; 1IOC; 1IP1; 1IP2; 1IP3; 1IP4; 1IP5; 1IP6; 1IP7; 1IWT; 1IWU; 1IWV; 1IWW; 1IWX; 1IWY; 1IWZ; 1IX0; 1IY3; 1IY4; 1JKA; 1JKB; 1JKC; 1JKD; 1JSF; 1JWR; 1LAA; 1LHH; 1LHI; 1LHJ; 1LHK; 1LHL; 1LHM; 1LMT; 1LOZ; 1LYY; 1LZ1; 1LZ4; 1LZ5; 1LZ6; 1LZR; 1LZS; 1OP9; 1OUA; 1OUB; 1OUC; 1OUD; 1OUE; 1OUF; 1OUG; 1OUH; 1OUI; 1OUJ; 1QSW; 1RE2; 1REM; 1REX; 1REY; 1REZ; 1TAY; 1TBY; 1TCY; 1TDY; 1UBZ; 1W08; 1WQM; 1WQN; 1WQO; 1WQP; 1WQQ; 1WQR; 1YAM; 1YAN; 1YAO; 1YAP; 1YAQ; 207L; 208L; 2BQA; 2BQB; 2BQC; 2BQD; 2BQE; 2BQF; 2BQG; 2BQH; 2BQI; 2BQJ; 2BQK; 2BQL; 2BQM; 2BQN; 2BQO; 2HEA; 2HEB; 2HEC; 2HED; 2HEE; 2HEF; 2LHM; 2MEA; 2MEB; 2MEC; 2MED; 2MEE; 2MEF; 2MEG; 2MEH; 2MEI; 2NWD; 2ZIJ; 2ZIK; 2ZIL; 2ZWB; 3EBA; 3FE0; 3LHM; 3LN2; 4I0C; 4ML7; 4R0P

14 known interactions (drugs) of input target (LYZ): Lysozyme C
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter
1 Experimental SmallMoleculeDrug DB03013 Di(N-Acetyl-D-Glucosamine) Thumb
2 Experimental SmallMoleculeDrug DB06912 UNDECA-3,7-DIENE-1,3,7,11-TETRACARBALDEHYDE Thumb
3 Experimental SmallMoleculeDrug DB03189 Cu-Cyclam Thumb
4 Approved;
SmallMoleculeDrug DB00128 L-Aspartic Acid Thumb
5 Approved;
SmallMoleculeDrug DB02772 Sucrose Thumb
6 Experimental SmallMoleculeDrug DB03487 3-Aminosuccinimide Thumb
7 Experimental SmallMoleculeDrug DB02759 4-Methylumbelliferyl Chitobiose Thumb
8 Experimental SmallMoleculeDrug DB04268 Methylumbelliferyl Chitotriose Thumb
9 Experimental SmallMoleculeDrug DB03120 Para-Toluene Sulfonate Thumb
10 Experimental SmallMoleculeDrug DB04194 Chitotriose Thumb
11 Experimental;
Vet approved
SmallMoleculeDrug DB03006 Arsanilic acid Thumb
12 Experimental SmallMoleculeDrug DB03967 Dodecyl Sulfate Thumb
13 Experimental SmallMoleculeDrug DB02159 (R)-Propylene glycol Thumb
14 Approved;
SmallMoleculeDrug DB03175 Propyl alcohol Thumb

20 predicted interactions (drugs) of input target (LYZ): Lysozyme C
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter
Image Confidence score
1 Approved;
SmallMoleculeDrug DB00157 NADH Thumb 46.4%
2 Approved;
SmallMoleculeDrug DB00172 L-Proline Thumb 28.5%
3 Approved;
SmallMoleculeDrug DB11633 Isavuconazole Thumb 25.9%
4 Approved;
SmallMoleculeDrug DB00142 Glutamic Acid Thumb 24.0%
5 Approved;
SmallMoleculeDrug DB03796 Palmitic Acid Thumb 21.9%
6 Approved;
SmallMoleculeDrug DB00716 Nedocromil Thumb 21.5%
7 Experimental SmallMoleculeDrug DB03616 Kabiramide C Thumb 21.5%
8 Experimental SmallMoleculeDrug DB04775 Reidispongiolide C Thumb 21.3%
9 Experimental SmallMoleculeDrug DB07272 N-(4-AMINO-5-CYANO-6-ETHOXYPYRIDIN-2-YL)-2-(4-BROMO-2,5-DIMETHOXYPHENYL)ACETAMIDE Thumb 20.3%
10 Approved BiotechDrug DB11311 Prothrombin Thumb 20.2%
11 Investigational SmallMoleculeDrug DB05032 REV131 Thumb 20.1%
12 Experimental SmallMoleculeDrug DB04661 Cis-tetracosenoyl sulfatide Thumb 20.0%
13 Approved SmallMoleculeDrug DB01016 Glyburide Thumb 19.7%
14 Investigational SmallMoleculeDrug DB05945 MDX-1303 Thumb 19.4%
15 Approved SmallMoleculeDrug DB03147 Flavin adenine dinucleotide Thumb 19.3%
16 Approved;
SmallMoleculeDrug DB00786 Marimastat Thumb 18.9%
17 Approved;
SmallMoleculeDrug DB05389 Tetrachlorodecaoxide Thumb 18.9%
18 Experimental SmallMoleculeDrug DB07930 (3R)-3-HYDROXYDODECANOIC ACID Thumb 18.8%
19 Experimental SmallMoleculeDrug DB02932 (R)-Bicalutamide Thumb 18.3%
20 Investigational BiotechDrug DB06226 Nelipepimut-S Thumb 18.3%


Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.


The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.