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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: P98194
No. Gene UniProt ID Protein Name Pathway PDB
1 ATP2C1 P98194 Calcium-transporting ATPase type 2C member 1 NA NA


7 known interactions (drugs) of input target (ATP2C1): Calcium-transporting ATPase type 2C member 1
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image
1 Approved;
Vet approved		 SmallMoleculeDrug DB00753 Isoflurane Thumb
2 Approved;
Investigational;
Vet approved		 SmallMoleculeDrug DB00228 Enflurane Thumb
3 Approved;
Nutraceutical		 SmallMoleculeDrug DB01373 Calcium Thumb
4 Approved;
Vet approved		 SmallMoleculeDrug DB01236 Sevoflurane Thumb
5 Approved;
Investigational;
Vet approved		 SmallMoleculeDrug DB01028 Methoxyflurane Thumb
6 Approved;
Vet approved		 SmallMoleculeDrug DB01159 Halothane Thumb
7 Approved SmallMoleculeDrug DB01189 Desflurane Thumb


20 predicted interactions (drugs) of input target (ATP2C1): Calcium-transporting ATPase type 2C member 1
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image Confidence score
1 Approved SmallMoleculeDrug DB00898 Ethanol Thumb 60.8%
2 Approved;
Investigational		 SmallMoleculeDrug DB00334 Olanzapine Thumb 58.9%
3 Approved SmallMoleculeDrug DB00273 Topiramate Thumb 58.1%
4 Approved SmallMoleculeDrug DB00543 Amoxapine Thumb 57.5%
5 Approved;
Investigational		 SmallMoleculeDrug DB00555 Lamotrigine Thumb 57.3%
6 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB01708 Prasterone Thumb 56.3%
7 Approved SmallMoleculeDrug DB00292 Etomidate Thumb 54.6%
8 Approved;
Nutraceutical		 SmallMoleculeDrug DB01956 Taurine Thumb 54.3%
9 Approved SmallMoleculeDrug DB09118 Stiripentol Thumb 53.2%
10 Approved;
Investigational		 SmallMoleculeDrug DB11901 Apalutamide Thumb 53.2%
11 Approved;
Illicit		 SmallMoleculeDrug DB00371 Meprobamate Thumb 53.0%
12 Approved;
Illicit		 SmallMoleculeDrug DB00628 Clorazepate Thumb 52.7%
13 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB01381 Ginkgo biloba Thumb 52.6%
14 Approved;
Investigational		 SmallMoleculeDrug DB11582 Thiocolchicoside Thumb 52.5%
15 Approved;
Investigational;
Vet approved		 SmallMoleculeDrug DB00818 Propofol Thumb 52.5%
16 Approved;
Illicit		 SmallMoleculeDrug DB01437 Glutethimide Thumb 52.3%
17 Approved;
Illicit		 SmallMoleculeDrug DB00306 Talbutal Thumb 52.2%
18 Approved;
Investigational		 SmallMoleculeDrug DB00659 Acamprosate Thumb 51.6%
19 Approved;
Illicit		 SmallMoleculeDrug DB01068 Clonazepam Thumb 51.5%
20 Approved;
Illicit;
Withdrawn		 SmallMoleculeDrug DB00189 Ethchlorvynol Thumb 50.9%


  logl

Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.

Contact:

The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.