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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: P34972
No. Gene UniProt ID Protein Name Pathway PDB
1 CNR2 P34972 Cannabinoid receptor 2 hsa04080 2KI9


8 known interactions (drugs) of input target (CNR2): Cannabinoid receptor 2
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image
1 Approved;
Illicit		 SmallMoleculeDrug DB00470 Dronabinol Thumb
2 Experimental;
Investigational		 BiotechDrug DB14009 Medical Cannabis Thumb
3 Experimental SmallMoleculeDrug DB02955 Ricinoleic Acid Thumb
4 Investigational SmallMoleculeDrug DB11755 Tetrahydrocannabivarin Thumb
5 Approved;
Investigational		 SmallMoleculeDrug DB14011 Nabiximols Thumb
6 Approved;
Investigational		 SmallMoleculeDrug DB09061 Cannabidiol Thumb
7 Approved;
Investigational		 SmallMoleculeDrug DB06202 Lasofoxifene Thumb
8 Approved;
Investigational		 SmallMoleculeDrug DB00486 Nabilone Thumb


20 predicted interactions (drugs) of input target (CNR2): Cannabinoid receptor 2
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image Confidence score
1 Investigational SmallMoleculeDrug DB14050 Cannabidivarin Thumb 44.2%
2 Approved;
Investigational		 SmallMoleculeDrug DB06155 Rimonabant Thumb 42.9%
3 Approved;
Investigational		 SmallMoleculeDrug DB09288 Propacetamol Thumb 40.8%
4 Approved SmallMoleculeDrug DB01744 Camphor Thumb 40.1%
5 Investigational SmallMoleculeDrug DB05077 SLV319 Thumb 37.3%
6 Experimental SmallMoleculeDrug DB11345 (S)-camphor Thumb 36.0%
7 Investigational SmallMoleculeDrug DB05201 V24343 Thumb 34.2%
8 Approved SmallMoleculeDrug DB00825 Menthol Thumb 33.3%
9 Investigational SmallMoleculeDrug DB05372 CP-945598 Thumb 31.6%
10 Investigational SmallMoleculeDrug DB05750 AVE-1625 Thumb 30.0%
11 Approved;
Withdrawn		 SmallMoleculeDrug DB11148 Butamben Thumb 28.5%
12 Approved SmallMoleculeDrug DB09089 Trimebutine Thumb 27.1%
13 Approved;
Vet approved		 SmallMoleculeDrug DB01221 Ketamine Thumb 26.7%
14 Approved;
Investigational;
Vet approved		 SmallMoleculeDrug DB01392 Yohimbine Thumb 26.0%
15 Investigational SmallMoleculeDrug DB11324 Nonivamide Thumb 25.2%
16 Approved SmallMoleculeDrug DB09086 Eugenol Thumb 23.8%
17 Approved;
Investigational		 SmallMoleculeDrug DB00568 Cinnarizine Thumb 23.1%
18 Investigational SmallMoleculeDrug DB05885 Seletracetam Thumb 22.4%
19 Approved;
Experimental		 SmallMoleculeDrug DB13746 Bioallethrin Thumb 22.3%
20 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB09270 Ubidecarenone Thumb 22.0%


  logl

Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.

Contact:

The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.