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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Results:

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Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: P35354

No.	Gene	UniProt ID	Protein Name	Pathway	PDB
1	PTGS2	P35354	Prostaglandin G/H synthase 2	hsa00590; hsa01100; hsa04064; hsa04370; hsa04625; hsa04657; hsa04668; hsa04723; hsa04726; hsa04913; hsa04921; hsa04923; hsa05140; hsa05163; hsa05165; hsa05167; hsa05200; hsa05204; hsa05206; hsa05222	1V0X

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Image
1	Approved	SmallMoleculeDrug	DB01600	Tiaprofenic acid	CC(C(O)=O)C1=CC=C(S1)C(=O)C1=CC=CC=C1
2	Approved	SmallMoleculeDrug	DB00795	Sulfasalazine	OC(=O)C1=CC(=CC=C1O)\N=N\C1=CC=C(C=C1)S(=O)(=O)NC1=NC=CC=C1
3	Approved; Vet approved	SmallMoleculeDrug	DB00945	Acetylsalicylic acid	CC(=O)OC1=CC=CC=C1C(O)=O
4	Approved	SmallMoleculeDrug	DB00784	Mefenamic acid	CC1=C(C)C(NC2=CC=CC=C2C(O)=O)=CC=C1
5	Approved; Vet approved	SmallMoleculeDrug	DB00586	Diclofenac	OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl
6	Approved; Investigational	SmallMoleculeDrug	DB09288	Propacetamol	CCN(CC)CC(=O)OC1=CC=C(NC(C)=O)C=C1
7	Approved; Vet approved; Withdrawn	SmallMoleculeDrug	DB00821	Carprofen	CC(C(O)=O)C1=CC2=C(C=C1)C1=C(N2)C=CC(Cl)=C1
8	Approved	SmallMoleculeDrug	DB08439	Parecoxib	CCC(=O)NS(=O)(=O)C1=CC=C(C=C1)C1=C(C)ON=C1C1=CC=CC=C1
9	Experimental; Vet approved	SmallMoleculeDrug	DB09217	Firocoxib	CC1(C)OC(=O)C(OCC2CC2)=C1C1=CC=C(C=C1)S(C)(=O)=O
10	Approved; Investigational; Nutraceutical	SmallMoleculeDrug	DB00154	Dihomo-gamma-linolenic acid	CCCCC\C=C/C\C=C/C\C=C/CCCCCCC(O)=O
11	Approved	SmallMoleculeDrug	DB08910	Pomalidomide	NC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O
12	Approved	SmallMoleculeDrug	DB11327	Dipyrithione	[O-][N+]1=CC=CC=C1SSC1=CC=CC=[N+]1[O-]
13	Approved; Vet approved	SmallMoleculeDrug	DB00812	Phenylbutazone	CCCCC1C(=O)N(N(C1=O)C1=CC=CC=C1)C1=CC=CC=C1
14	Approved; Nutraceutical	SmallMoleculeDrug	DB13961	Fish oil	NA
15	Approved	SmallMoleculeDrug	DB01401	Choline magnesium trisalicylate	[Mg++].C[N+](C)(C)CCO.OC1=CC=CC=C1C([O-])=O.OC1=CC=CC=C1C([O-])=O.OC1=CC=CC=C1C([O-])=O
16	Approved	SmallMoleculeDrug	DB01397	Magnesium salicylate	[Mg++].OC1=CC=CC=C1C([O-])=O.OC1=CC=CC=C1C([O-])=O
17	Approved; Investigational	SmallMoleculeDrug	DB00328	Indomethacin	COC1=CC2=C(C=C1)N(C(=O)C1=CC=C(Cl)C=C1)C(C)=C2CC(O)=O
18	Approved; Investigational	SmallMoleculeDrug	DB09213	Dexibuprofen	[H][C@@](C)(C(O)=O)C1=CC=C(CC(C)C)C=C1
19	Experimental	SmallMoleculeDrug	DB03866	Prostaglandin G2	[H][C@@](CCCCC)(OO)\C=C\[C@@]1([H])[C@@]2([H])C[C@]([H])(OO2)[C@]1([H])C\C=C/CCCC(O)=O
20	Approved	SmallMoleculeDrug	DB09285	Morniflumate	FC(F)(F)C1=CC(NC2=C(C=CC=N2)C(=O)OCCN2CCOCC2)=CC=C1
21	Approved	SmallMoleculeDrug	DB11079	Trolamine salicylate	OCCN(CCO)CCO.OC(=O)C1=CC=CC=C1O
22	Approved	SmallMoleculeDrug	DB11071	Phenyl salicylate	OC1=CC=CC=C1C(=O)OC1=CC=CC=C1
23	Approved; Experimental	SmallMoleculeDrug	DB13346	Bufexamac	CCCCOC1=CC=C(CC(=O)NO)C=C1
24	Approved	SmallMoleculeDrug	DB00469	Tenoxicam	CN1C(C(=O)NC2=CC=CC=N2)=C(O)C2=C(C=CS2)S1(=O)=O
25	Approved; Experimental; Investigational	SmallMoleculeDrug	DB13783	Acemetacin	COC1=CC2=C(C=C1)N(C(=O)C1=CC=C(Cl)C=C1)C(C)=C2CC(=O)OCC(O)=O
26	Experimental	SmallMoleculeDrug	DB03477	1-Phenylsulfonamide-3-Trifluoromethyl-5-Parabromophenylpyrazole	NS(=O)(=O)C1=CC=C(C=C1)N1N=C(C=C1C1=CC=C(Br)C=C1)C(F)(F)F
27	Approved; Investigational	SmallMoleculeDrug	DB01014	Balsalazide	OC(=O)CCNC(=O)C1=CC=C(C=C1)\N=N\C1=CC=C(O)C(=C1)C(O)=O
28	Experimental	SmallMoleculeDrug	DB02266	Flufenamic Acid	OC(=O)C1=CC=CC=C1NC1=CC(=CC=C1)C(F)(F)F
29	Approved; Investigational	SmallMoleculeDrug	DB00554	Piroxicam	CN1C(C(=O)NC2=NC=CC=C2)=C(O)C2=C(C=CC=C2)S1(=O)=O
30	Approved	SmallMoleculeDrug	DB00991	Oxaprozin	OC(=O)CCC1=NC(=C(O1)C1=CC=CC=C1)C1=CC=CC=C1
31	Approved; Investigational	SmallMoleculeDrug	DB09216	Tolfenamic Acid	CC1=C(Cl)C=CC=C1NC1=CC=CC=C1C(O)=O
32	Approved	SmallMoleculeDrug	DB00573	Fenoprofen	CC(C(O)=O)C1=CC(OC2=CC=CC=C2)=CC=C1
33	Approved; Investigational	SmallMoleculeDrug	DB00605	Sulindac	CC1=C(CC(O)=O)C2=CC(F)=CC=C2\C1=C/C1=CC=C(C=C1)S(C)=O
34	Approved; Vet approved	SmallMoleculeDrug	DB00788	Naproxen	COC1=CC2=C(C=C1)C=C(C=C2)[C@H](C)C(O)=O
35	Approved	SmallMoleculeDrug	DB00244	Mesalazine	NC1=CC(C(O)=O)=C(O)C=C1
36	Approved; Vet approved	SmallMoleculeDrug	DB00939	Meclofenamic acid	CC1=C(Cl)C(NC2=CC=CC=C2C(O)=O)=C(Cl)C=C1
37	Approved; Investigational; Vet approved	SmallMoleculeDrug	DB00936	Salicylic acid	OC(=O)C1=CC=CC=C1O
38	Approved; Investigational	SmallMoleculeDrug	DB01283	Lumiracoxib	CC1=CC=C(NC2=C(Cl)C=CC=C2F)C(CC(O)=O)=C1
39	Approved; Vet approved	SmallMoleculeDrug	DB00814	Meloxicam	CN1C(C(=O)NC2=NC=C(C)S2)=C(O)C2=C(C=CC=C2)S1(=O)=O
40	Approved	SmallMoleculeDrug	DB00500	Tolmetin	CN1C(CC(O)=O)=CC=C1C(=O)C1=CC=C(C)C=C1
41	Approved; Investigational	SmallMoleculeDrug	DB09212	Loxoprofen	CC(C(O)=O)C1=CC=C(CC2CCCC2=O)C=C1
42	Approved; Investigational	SmallMoleculeDrug	DB06802	Nepafenac	NC(=O)CC1=CC=CC(C(=O)C2=CC=CC=C2)=C1N
43	Approved; Investigational	SmallMoleculeDrug	DB01435	Antipyrine	CN1N(C(=O)C=C1C)C1=CC=CC=C1
44	Approved; Nutraceutical	SmallMoleculeDrug	DB00159	Icosapent	CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O
45	Approved; Investigational; Withdrawn	SmallMoleculeDrug	DB00580	Valdecoxib	CC1=C(C(=NO1)C1=CC=CC=C1)C1=CC=C(C=C1)S(N)(=O)=O
46	Approved; Investigational; Nutraceutical	SmallMoleculeDrug	DB01404	Ginseng	NA
47	Approved	SmallMoleculeDrug	DB01050	Ibuprofen	CC(C)CC1=CC=C(C=C1)C(C)C(O)=O
48	Approved	SmallMoleculeDrug	DB00480	Lenalidomide	NC1=CC=CC2=C1CN(C1CCC(=O)NC1=O)C2=O
49	Approved; Investigational	SmallMoleculeDrug	DB00861	Diflunisal	OC(=O)C1=C(O)C=CC(=C1)C1=C(F)C=C(F)C=C1
50	Withdrawn	SmallMoleculeDrug	DB09215	Droxicam	CN1C2=C(OC(=O)N(C2=O)C2=CC=CC=N2)C2=CC=CC=C2S1(=O)=O
51	Approved; Investigational; Withdrawn	SmallMoleculeDrug	DB04743	Nimesulide	CS(=O)(=O)NC1=C(OC2=CC=CC=C2)C=C(C=C1)[N+]([O-])=O
52	Approved; Investigational	SmallMoleculeDrug	DB06736	Aceclofenac	OC(=O)COC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl
53	Approved; Investigational; Withdrawn	SmallMoleculeDrug	DB01041	Thalidomide	O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC=CC=C12
54	Approved	SmallMoleculeDrug	DB11201	Menthyl salicylate	CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OC(=O)C1=CC=CC=C1O
55	Approved	SmallMoleculeDrug	DB00963	Bromfenac	NC1=C(CC(O)=O)C=CC=C1C(=O)C1=CC=C(Br)C=C1
56	Approved; Investigational	SmallMoleculeDrug	DB00712	Flurbiprofen	CC(C(O)=O)C1=CC(F)=C(C=C1)C1=CC=CC=C1
57	Approved	SmallMoleculeDrug	DB11323	Glycol salicylate	OCCOC(=O)C1=CC=CC=C1O
58	Approved; Investigational	SmallMoleculeDrug	DB06725	Lornoxicam	CN1C(C(=O)NC2=CC=CC=N2)=C(O)C2=C(C=C(Cl)S2)S1(=O)=O
59	Approved; Investigational	SmallMoleculeDrug	DB01628	Etoricoxib	CC1=NC=C(C=C1)C1=C(C=C(Cl)C=N1)C1=CC=C(C=C1)S(C)(=O)=O
60	Approved; Investigational; Withdrawn	SmallMoleculeDrug	DB00533	Rofecoxib	CS(=O)(=O)C1=CC=C(C=C1)C1=C(C(=O)OC1)C1=CC=CC=C1
61	Approved	SmallMoleculeDrug	DB00461	Nabumetone	COC1=CC2=C(C=C1)C=C(CCC(C)=O)C=C2
62	Approved; Vet approved	SmallMoleculeDrug	DB01009	Ketoprofen	CC(C(O)=O)C1=CC(=CC=C1)C(=O)C1=CC=CC=C1
63	Approved; Investigational	SmallMoleculeDrug	DB00482	Celecoxib	CC1=CC=C(C=C1)C1=CC(=NN1C1=CC=C(C=C1)S(N)(=O)=O)C(F)(F)F
64	Approved	SmallMoleculeDrug	DB00233	Aminosalicylic Acid	NC1=CC(O)=C(C=C1)C(O)=O
65	Investigational	SmallMoleculeDrug	DB04725	Licofelone	CC1(C)CN2C(CC(O)=O)=C(C(=C2C1)C1=CC=CC=C1)C1=CC=C(Cl)C=C1
66	Approved	SmallMoleculeDrug	DB04552	Niflumic Acid	OC(=O)C1=C(NC2=CC=CC(=C2)C(F)(F)F)N=CC=C1
67	Approved	SmallMoleculeDrug	DB00465	Ketorolac	OC(=O)C1CCN2C1=CC=C2C(=O)C1=CC=CC=C1
68	Approved	SmallMoleculeDrug	DB01399	Salsalate	OC(=O)C1=CC=CC=C1OC(=O)C1=CC=CC=C1O
69	Approved	SmallMoleculeDrug	DB01419	Antrafenine	FC(F)(F)C1=CC(=CC=C1)N1CCN(CCOC(=O)C2=CC=CC=C2NC2=C3C=CC(=CC3=NC=C2)C(F)(F)F)CC1
70	Approved; Experimental; Investigational	SmallMoleculeDrug	DB02709	Resveratrol	OC1=CC=C(\C=C\C2=CC(O)=CC(O)=C2)C=C1
71	Approved	SmallMoleculeDrug	DB00316	Acetaminophen	CC(=O)NC1=CC=C(O)C=C1
72	Approved; Investigational	SmallMoleculeDrug	DB09214	Dexketoprofen	[H][C@@](C)(C(O)=O)C1=CC(=CC=C1)C(=O)C1=CC=CC=C1
73	Approved; Withdrawn	SmallMoleculeDrug	DB00870	Suprofen	CC(C(O)=O)C1=CC=C(C=C1)C(=O)C1=CC=CS1
74	Investigational	SmallMoleculeDrug	DB05095	Cimicoxib	COC1=C(F)C=C(C=C1)C1=C(Cl)N=CN1C1=CC=C(C=C1)S(N)(=O)=O
75	Approved	SmallMoleculeDrug	DB09295	Talniflumate	FC(F)(F)C1=CC(NC2=C(C=CC=N2)C(=O)OC2OC(=O)C3=CC=CC=C23)=CC=C1
76	Approved	SmallMoleculeDrug	DB00210	Adapalene	COC1=C(C=C(C=C1)C1=CC2=C(C=C1)C=C(C=C2)C(O)=O)C12CC3CC(CC(C3)C1)C2
77	Approved; Investigational; Vet approved	SmallMoleculeDrug	DB00749	Etodolac	CCC1=C2NC3=C(CCOC3(CC)CC(O)=O)C2=CC=C1
78	Approved; Withdrawn	SmallMoleculeDrug	DB13167	Alclofenac	OC(=O)CC1=CC(Cl)=C(OCC=C)C=C1

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Image	Confidence score
1	Investigational	SmallMoleculeDrug	DB12445	Nitroaspirin	CC(=O)OC1=CC=CC=C1C(=O)OC1=CC=CC(CO[N+]([O-])=O)=C1		70.9%
2	Approved; Investigational	SmallMoleculeDrug	DB00350	Minoxidil	NC1=CC(=NC(N)=[N+]1[O-])N1CCCCC1		70.5%
3	Experimental	SmallMoleculeDrug	DB07983	1-(4-IODOBENZOYL)-5-METHOXY-2-METHYL INDOLE-3-ACETIC ACID	COC1=CC=C2N(C(=O)C3=CC=C(I)C=C3)C(C)=C(CC(O)=O)C2=C1		68.7%
4	Experimental	SmallMoleculeDrug	DB02110	Protoporphyrin Ix Containing Co	CC1=C(CCC(O)=O)C2=CC3=C(CCC(O)=O)C(C)=C4C=C5N6C(=CC7=C(C=C)C(C)=C8C=C1N2[Co]6(N34)N78)C(C)=C5C=C		68.4%
5	Withdrawn	SmallMoleculeDrug	DB03783	Phenacetin	CCOC1=CC=C(NC(C)=O)C=C1		67.8%
6	Experimental	SmallMoleculeDrug	DB02773	(3-Chloro-4-Propoxy-Phenyl)-Acetic Acid	CCCOC1=CC=C(CC(O)=O)C=C1Cl		67.2%
7	Experimental	SmallMoleculeDrug	DB07981	2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-n-[(1R)-1-(hydroxymethyl)propyl]acetamide	CC[C@H](CO)NC(=O)CC1=C(C)N(C(=O)C2=CC=C(Cl)C=C2)C2=CC=C(OC)C=C12		66.0%
8	Experimental	SmallMoleculeDrug	DB02198	2-Bromoacetyl Group	OC(=O)CBr		65.5%
9	Experimental	SmallMoleculeDrug	DB02047	2-(1,1'-Biphenyl-4-Yl)Propanoic Acid	[H][C@@](C)(C(O)=O)C1=CC=C(C=C1)C1=CC=CC=C1		65.1%
10	Nutraceutical	SmallMoleculeDrug	DB01892	Hyperforin	CC(C)C(=O)[C@@]12C(O)=C(CC=C(C)C)C(=O)[C@@](CC=C(C)C)(C[C@H](CC=C(C)C)[C@@]1(C)CCC=C(C)C)C2=O		64.3%
11	Experimental	SmallMoleculeDrug	DB02379	Beta-D-Glucose	OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O		63.8%
12	Approved; Investigational	SmallMoleculeDrug	DB08814	Triflusal	CC(=O)OC1=C(C=CC(=C1)C(F)(F)F)C(O)=O		63.3%
13	Experimental	SmallMoleculeDrug	DB04557	Arachidonic Acid	CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O		62.9%
14	Approved; Investigational; Withdrawn	SmallMoleculeDrug	DB04817	Metamizole	[Na+].CN(CS([O-])(=O)=O)C1=C(C)N(C)N(C1=O)C1=CC=CC=C1		62.8%
15	Experimental	SmallMoleculeDrug	DB03753	Flurbiprofen Methyl Ester	COC(=O)[C@@H](C)C1=CC=C(C(F)=C1)C1=CC=CC=C1		62.6%
16	Experimental	SmallMoleculeDrug	DB03752	P-(2'-Iodo-5'-Thenoyl)Hydrotropic Acid	[H][C@@](C)(C(O)=O)C1=CC=C(C=C1)C(=O)C1=CC=C(I)S1		61.8%
17	Experimental	SmallMoleculeDrug	DB07984	2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-n-[(1S)-1-(hydroxymethyl)propyl]acetamide	CC[C@@H](CO)NC(=O)CC1=C(C)N(C(=O)C2=CC=C(Cl)C=C2)C2=C1C=C(OC)C=C2		61.4%
18	Approved; Investigational; Vet approved	SmallMoleculeDrug	DB00711	Diethylcarbamazine	CCN(CC)C(=O)N1CCN(C)CC1		61.0%
19	Experimental	SmallMoleculeDrug	DB03667	Acetic Acid Salicyloyl-Amino-Ester	CC(=O)ONC(=O)C1=C(O)C=CC=C1		60.1%
20	Experimental	SmallMoleculeDrug	DB01837	O-acetyl-L-serine	CC(=O)OC[C@H](N)C(O)=O		59.7%