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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: P48167
No. Gene UniProt ID Protein Name Pathway PDB
1 GLRB P48167 Glycine receptor subunit beta hsa04080 NA


7 known interactions (drugs) of input target (GLRB): Glycine receptor subunit beta
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image
1 Investigational SmallMoleculeDrug DB05885 Seletracetam Thumb
2 Experimental;
Investigational		 BiotechDrug DB14009 Medical Cannabis Thumb
3 Approved;
Withdrawn		 SmallMoleculeDrug DB00431 Lindane Thumb
4 Approved;
Investigational;
Vet approved		 SmallMoleculeDrug DB00228 Enflurane Thumb
5 Approved;
Investigational		 SmallMoleculeDrug DB14011 Nabiximols Thumb
6 Approved;
Nutraceutical;
Vet approved		 SmallMoleculeDrug DB00145 Glycine Thumb
7 Approved;
Investigational		 SmallMoleculeDrug DB09061 Cannabidiol Thumb


20 predicted interactions (drugs) of input target (GLRB): Glycine receptor subunit beta
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image Confidence score
1 Experimental SmallMoleculeDrug DB00466 Picrotoxin Thumb 52.2%
2 Investigational SmallMoleculeDrug DB11755 Tetrahydrocannabivarin Thumb 47.4%
3 Approved;
Investigational;
Vet approved		 SmallMoleculeDrug DB00602 Ivermectin Thumb 45.6%
4 Approved;
Vet approved		 SmallMoleculeDrug DB00572 Atropine Thumb 44.4%
5 Approved SmallMoleculeDrug DB09089 Trimebutine Thumb 43.6%
6 Approved;
Nutraceutical		 SmallMoleculeDrug DB01956 Taurine Thumb 42.8%
7 Approved;
Vet approved		 SmallMoleculeDrug DB00753 Isoflurane Thumb 42.7%
8 Approved;
Vet approved		 SmallMoleculeDrug DB01236 Sevoflurane Thumb 42.6%
9 Approved SmallMoleculeDrug DB00898 Ethanol Thumb 42.4%
10 Approved;
Investigational		 SmallMoleculeDrug DB11582 Thiocolchicoside Thumb 41.5%
11 Approved;
Vet approved		 SmallMoleculeDrug DB01159 Halothane Thumb 39.9%
12 Approved SmallMoleculeDrug DB01189 Desflurane Thumb 39.3%
13 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB01708 Prasterone Thumb 38.2%
14 Approved;
Investigational;
Vet approved		 SmallMoleculeDrug DB01028 Methoxyflurane Thumb 37.4%
15 Approved;
Illicit		 SmallMoleculeDrug DB00306 Talbutal Thumb 36.2%
16 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB01381 Ginkgo biloba Thumb 35.4%
17 Approved;
Investigational		 SmallMoleculeDrug DB00555 Lamotrigine Thumb 34.6%
18 Approved SmallMoleculeDrug DB00543 Amoxapine Thumb 34.2%
19 Investigational SmallMoleculeDrug DB05417 GW 468816 Thumb 34.0%
20 Approved;
Illicit		 SmallMoleculeDrug DB00241 Butalbital Thumb 33.0%


  logl

Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.

Contact:

The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.