QuartataWeb 1.0

13 known interactions (drugs) of input target (NFKB1): Nuclear factor NF-kappa-B p105 subunit

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter
1	Approved; Investigational	SmallMoleculeDrug	DB01411	Pranlukast	O=C(NC1=C2OC(=CC(=O)C2=CC=C1)C1=NNN=N1)C1=CC=C(OCCCCC2=CC=CC=C2)C=C1
2	Approved; Vet approved	SmallMoleculeDrug	DB00945	Acetylsalicylic acid	CC(=O)OC1=CC=CC=C1C(O)=O
3	Experimental; Investigational	SmallMoleculeDrug	DB14059	SC-236	NS(=O)(=O)C1=CC=C(C=C1)N1N=C(C=C1C1=CC=C(Cl)C=C1)C(F)(F)F
4	Approved; Investigational	SmallMoleculeDrug	DB08814	Triflusal	CC(=O)OC1=C(C=CC(=C1)C(F)(F)F)C(O)=O
5	Investigational	SmallMoleculeDrug	DB05451	P54	NA
6	Approved; Experimental	SmallMoleculeDrug	DB13751	Glycyrrhizic acid	[H][C@@]12C[C@](C)(CC[C@]1(C)CC[C@]1(C)C2=CC(=O)[C@]2([H])[C@@]3(C)CC[C@H](O[C@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O[C@@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)C(O)=O)C(O)=O)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O
7	Investigational	SmallMoleculeDrug	DB05487	Custirsen	NA
8	Approved; Investigational; Withdrawn	SmallMoleculeDrug	DB01041	Thalidomide	O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC=CC=C12
9	Investigational	SmallMoleculeDrug	DB05212	HE3286	C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@]2(O)C#C)[C@@H](O)C=C1C[C@@H](O)CC[C@]31C
10	Approved; Nutraceutical	SmallMoleculeDrug	DB13961	Fish oil	NA
11	Investigational	SmallMoleculeDrug	DB05464	NOX-700	NA
12	Investigational	BiotechDrug	DB05471	SGN-30	NA
13	Investigational	SmallMoleculeDrug	DB05767	Andrographolide	[H]\C(C[C@]1([H])C(=C)CC[C@]2([H])[C@](C)(CO)[C@]([H])(O)CC[C@@]12C)=C1/C(=O)OC[C@@]1([H])O

20 predicted interactions (drugs) of input target (NFKB1): Nuclear factor NF-kappa-B p105 subunit

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Confidence score
1	Approved; Investigational	SmallMoleculeDrug	DB01296	Glucosamine	N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O	54.1%
2	Experimental	SmallMoleculeDrug	DB04464	N-Formylmethionine	[H][C@@](CCSC)(NC=O)C(O)=O	30.9%
3	Approved; Investigational; Nutraceutical	SmallMoleculeDrug	DB00143	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O	30.8%
4	Approved	SmallMoleculeDrug	DB00458	Imipramine	CN(C)CCCN1C2=CC=CC=C2CCC2=CC=CC=C12	27.6%
5	Approved	SmallMoleculeDrug	DB00244	Mesalazine	NC1=CC(C(O)=O)=C(O)C=C1	25.7%
6	Approved	SmallMoleculeDrug	DB01050	Ibuprofen	CC(C)CC1=CC=C(C=C1)C(C)C(O)=O	24.5%
7	Approved	SmallMoleculeDrug	DB08910	Pomalidomide	NC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O	24.4%
8	Approved	SmallMoleculeDrug	DB00316	Acetaminophen	CC(=O)NC1=CC=C(O)C=C1	22.9%
9	Approved	SmallMoleculeDrug	DB04855	Dronedarone	CCCCN(CCCC)CCCOC1=CC=C(C=C1)C(=O)C1=C(CCCC)OC2=C1C=C(NS(C)(=O)=O)C=C2	22.3%
10	Approved	SmallMoleculeDrug	DB00502	Haloperidol	OC1(CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1)C1=CC=C(Cl)C=C1	21.9%
11	Approved; Investigational	SmallMoleculeDrug	DB02701	Nicotinamide	NC(=O)C1=CC=CN=C1	21.9%
12	Experimental	SmallMoleculeDrug	DB07984	2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-n-[(1S)-1-(hydroxymethyl)propyl]acetamide	CC[C@@H](CO)NC(=O)CC1=C(C)N(C(=O)C2=CC=C(Cl)C=C2)C2=C1C=C(OC)C=C2	21.7%
13	Approved; Investigational	SmallMoleculeDrug	DB09213	Dexibuprofen	[H][C@@](C)(C(O)=O)C1=CC=C(CC(C)C)C=C1	21.6%
14	Experimental	SmallMoleculeDrug	DB04557	Arachidonic Acid	CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O	20.8%
15	Approved; Investigational	SmallMoleculeDrug	DB01014	Balsalazide	OC(=O)CCNC(=O)C1=CC=C(C=C1)\N=N\C1=CC=C(O)C(=C1)C(O)=O	20.0%
16	Experimental	SmallMoleculeDrug	DB03434	3[N-Morpholino]Propane Sulfonic Acid	OS(=O)(=O)CCCN1CCOCC1	19.9%
17	Approved	SmallMoleculeDrug	DB00469	Tenoxicam	CN1C(C(=O)NC2=CC=CC=N2)=C(O)C2=C(C=CS2)S1(=O)=O	19.9%
18	Investigational	SmallMoleculeDrug	DB05869	Ethyl pyruvate	CCOC(=O)C(C)=O	19.8%
19	Approved; Experimental	SmallMoleculeDrug	DB13346	Bufexamac	CCCCOC1=CC=C(CC(=O)NO)C=C1	19.7%
20	Approved; Experimental	SmallMoleculeDrug	DB13746	Bioallethrin	NA	19.7%