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Network of pathways (lightgreen rectangle) and targets (blue spheres) for the queried drug is displayed above.
Selecting nodes by clicking will fade out the nodes which are not connected to the selected nodes.

Data source: DrugBank-all; Query type: chemical; # of predictions: 20; Secondary interactions: no
Input drug 1: DB12445

5 pathways for known targets of input drug:
No. Pathway ID Pathway name Pathway Class 1 Pathway Class 2 Targets # of targets p-value (EPD) p-value (EPT)
1 hsa04611 Platelet activation Organismal Systems Immune system PTGS1 1 0.14 0.021
2 hsa04726 Serotonergic synapse Organismal Systems Nervous system PTGS1 1 0.17 0.021
3 hsa00590 Arachidonic acid metabolism Metabolism Lipid metabolism PTGS1 1 0.18 0.021
4 hsa04923 Regulation of lipolysis in adipocytes Organismal Systems Endocrine system PTGS1 1 0.14 0.021
5 hsa01100 Metabolic pathways Metabolism Global and overview maps PTGS1 1 0.27 0.17


Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.


The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.