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GO enrichment results  
   
Top 20 enriched GO molecular function (p-value based on targets)

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Data source: DrugBank-all; Query type: chemical; # of predictions: 20; Secondary interactions: no
Input drug 1: DB04864


9 GO molecular function of known targets for input drug:
No. GO terms Targets # of targets p-value (EPT)↑ p-value (EPD)
1 cholinesterase activity ACHE 1 0.0021 0.028
2 acetylcholinesterase activity ACHE 1 0.0021 0.028
3 serine hydrolase activity ACHE 1 0.0032 0.062
4 laminin binding ACHE 1 0.004 0.046
5 beta-amyloid binding ACHE 1 0.0051 0.037
6 hydrolase activity ACHE 1 0.0064 0.035
7 acetylcholine binding ACHE 1 0.0064 0.043
8 collagen binding ACHE 1 0.008 0.037
9 protein homodimerization activity ACHE 1 0.068 0.16


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Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.

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The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.