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GO enrichment results  
   
Top 20 enriched GO molecular function (p-value based on targets)

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Data source: DrugBank-all; Query type: chemical; # of predictions: 20; Secondary interactions: no
Input drug 1: DB07691


9 GO molecular function of known targets for input drug:
No. GO terms Targets # of targets p-value (EPT)↑ p-value (EPD)
1 linoleic acid binding PPARD 1 0.0032 0.039
2 lipid binding PPARD 1 0.022 0.13
3 steroid hormone receptor activity PPARD 1 0.022 0.14
4 sequence-specific DNA binding PPARD 1 0.027 0.13
5 drug binding PPARD 1 0.03 0.21
6 transcription factor activity, sequence-specific DNA binding PPARD 1 0.03 0.13
7 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding PPARD 1 0.03 0.15
8 DNA binding PPARD 1 0.034 0.13
9 zinc ion binding PPARD 1 0.07 0.21


  logl

Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.

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The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.