QuartataWeb 1.0

GO enrichment results

Top 20 enriched GO molecular function (p-value based on targets)

Results:

Data source: DrugBank-all; Query type: chemical; # of predictions: 20; Secondary interactions: no
Input drug 1: DB12200

4 GO molecular function of known targets for input drug:

No.	GO terms	Targets	# of targets	p-value (EPT)↑	p-value (EPD)
1	hepatocyte growth factor-activated receptor activity	MET	1	0.0014	0.01
2	protein phosphatase binding	MET	1	0.016	0.062
3	protein tyrosine kinase activity	MET	1	0.033	0.066
4	ATP binding	MET	1	0.2	0.24

Reference: Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.

Contact:

The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.