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GO enrichment results  
   
Top 20 enriched GO molecular function (p-value based on targets)

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Data source: DrugBank-all; Query type: chemical; # of predictions: 20; Secondary interactions: no
Input drug 1: DB02911


11 GO molecular function of known targets for input drug:
No. GO terms Targets # of targets p-value (EPT)↑ p-value (EPD)
1 NADPH-hemoprotein reductase activity NOS3 1 0.0039 0.034
2 arginine binding NOS3 1 0.0039 0.04
3 tetrahydrobiopterin binding NOS3 1 0.0039 0.034
4 actin monomer binding NOS3 1 0.0046 0.065
5 cadmium ion binding NOS3 1 0.0052 0.069
6 FMN binding NOS3 1 0.0056 0.039
7 nitric-oxide synthase activity NOS3 1 0.0059 0.05
8 NADP binding NOS3 1 0.01 0.039
9 flavin adenine dinucleotide binding NOS3 1 0.012 0.046
10 heme binding NOS3 1 0.024 0.084
11 iron ion binding NOS3 1 0.025 0.056


  logl

Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.

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The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.