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GO enrichment results  
   
Top 20 enriched GO molecular function (p-value based on targets)

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Data source: DrugBank-all; Query type: chemical; # of predictions: 20; Secondary interactions: no
Input drug 1: DB01251


7 GO molecular function of known targets for input drug:
No. GO terms Targets # of targets p-value (EPT)↑ p-value (EPD)
1 ATP-activated inward rectifier potassium channel activity KCNJ8 1 0.01 0.013
2 sulfonylurea receptor activity ABCC8 1 0.01 0.013
3 inward rectifier potassium channel activity KCNJ8 1 0.013 0.018
4 ATPase activity, coupled to transmembrane movement of substances ABCC8 1 0.013 0.015
5 potassium channel activity ABCC8 1 0.014 0.015
6 ion channel binding ABCC8 1 0.027 0.054
7 ATP binding KCNJ8;ABCC8 2 0.04 0.24


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Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.

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The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.