QuartataWeb
Home  |   About  |   Theory  |   Tutorials  |   FAQ  |   Bahar Lab  |   Statistics   |  Return to main result page

GO enrichment results  
   
Top 20 enriched GO molecular function (p-value based on targets)

Results: help


Download results

Data source: DrugBank-all; Query type: chemical; # of predictions: 20; Secondary interactions: no
Input drug 1: DB00245


10 GO molecular function of known targets for input drug:
No. GO terms Targets # of targets p-value (EPT) p-value (EPD)
1 dopamine transmembrane transporter activity SLC6A3 1 0.0053 0.041
2 dopamine SLC6A3 1 0.0053 0.041
3 histamine receptor activity HRH1 1 0.0089 0.052
4 monoamine transmembrane transporter activity SLC6A3 1 0.0089 0.048
5 G-protein coupled acetylcholine receptor activity CHRM1 1 0.011 0.047
6 histamine binding HRH1 1 0.011 0.059
7 dopamine binding SLC6A3 1 0.012 0.056
8 phosphatidylinositol phospholipase C activity CHRM1 1 0.015 0.047
9 G-protein coupled receptor activity HRH1 1 0.053 0.056
10 drug binding CHRM1 1 0.068 0.19



  logl

Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.

Contact:

The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.